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p53 status modifies cytotoxic activity of lactoferrin under hypoxic conditions
Lactoferrin (LF) is an iron binding glycoprotein of the transferrin family with a wide spectrum of biological effects, including anti-cancer activity. However, the detailed molecular mechanisms of anti-cancer activity of LF have not been fully determined. In this study, we tried to clarify cytotoxic...
Autores principales: | Kosim, Maryami Yuliana, Fukazawa, Takahiro, Miyauchi, Mutsumi, Hirohashi, Nobuyuki, Tanimoto, Keiji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527284/ https://www.ncbi.nlm.nih.gov/pubmed/36199689 http://dx.doi.org/10.3389/fphar.2022.988335 |
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