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Ectopic insert-dependent neuronal expression of GFAP promoter-driven AAV constructs in adult mouse retina

Direct reprogramming of retinal Müller glia is a promising avenue for replacing photoreceptors and retinal ganglion cells lost to retinal dystrophies. However, questions have recently been raised about the accuracy of studies claiming efficient glia-to-neuron reprogramming in retina that were conduc...

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Detalles Bibliográficos
Autores principales: Le, Nguyet, Appel, Haley, Pannullo, Nicole, Hoang, Thanh, Blackshaw, Seth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527291/
https://www.ncbi.nlm.nih.gov/pubmed/36200040
http://dx.doi.org/10.3389/fcell.2022.914386

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