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Interactions of marine sulfated glycans with antithrombin and platelet factor 4

The molecular interactions of sulfated glycans, such as heparin, with antithrombin (AT) and platelet factor 4 (PF4) are essential for certain biological events such as anticoagulation and heparin induced thrombocytopenia (HIT). In this study, a library including 84 sulfated glycans (polymers and oli...

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Detalles Bibliográficos
Autores principales: Zhang, Wenjing, Jin, Weihua, Pomin, Vitor H., Zhang, Fuming, Linhardt, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527323/
https://www.ncbi.nlm.nih.gov/pubmed/36200072
http://dx.doi.org/10.3389/fmolb.2022.954752