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Reduced RNA adenosine-to-inosine editing in hippocampus vasculature associated with Alzheimer’s disease

Alzheimer’s disease is the most common form of dementia and recent studies identify a type 1 interferon response in Alzheimer’s disease possibly driving neuro-inflammation and other Alzheimer’s disease pathologies. Loss of adenosine-to-inosine editing of endogenous Alu RNAs results in accumulation o...

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Detalles Bibliográficos
Autores principales:	Crooke, Philip S, Tossberg, John T, Heinrich, Rachel M, Porter, Krislyn P, Aune, Thomas M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527665/ https://www.ncbi.nlm.nih.gov/pubmed/36196083 http://dx.doi.org/10.1093/braincomms/fcac238

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