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The reduction of astrocytic tau prevents amyloid-β-induced synaptotoxicity

Alzheimer’s disease is a neurological disorder characterized by the overproduction and aggregation of amyloid-beta and the phosphorylation and intraneuronal accumulation of tau. These events promote synaptic dysfunction and loss, leading to neurodegeneration and cognitive deficits. Astrocytes are in...

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Detalles Bibliográficos
Autores principales:	Cisternas, Pablo, Taylor, Xavier, Martinez, Pablo, Maldonado, Orlando, Jury, Nur, Lasagna-Reeves, Cristian A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527666/ https://www.ncbi.nlm.nih.gov/pubmed/36196088 http://dx.doi.org/10.1093/braincomms/fcac235

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