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The Role of Endotracheal Tube in Medication-Related Osteonecrosis of the Jaw - A Case Report

RATIONALE: Various traumatic risk factors have been correlated to the development of medication-related osteonecrosis of the jaw (MRONJ), with long-term use of antiresorptive or antiangiogenic medications. No previous cases of MRONJ secondary to endotracheal intubation have been reported in the oral...

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Autores principales: Niloy, Injamamul L., Burkes, Jason N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527827/
https://www.ncbi.nlm.nih.gov/pubmed/36199473
http://dx.doi.org/10.4103/ams.ams_300_21
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author Niloy, Injamamul L.
Burkes, Jason N.
author_facet Niloy, Injamamul L.
Burkes, Jason N.
author_sort Niloy, Injamamul L.
collection PubMed
description RATIONALE: Various traumatic risk factors have been correlated to the development of medication-related osteonecrosis of the jaw (MRONJ), with long-term use of antiresorptive or antiangiogenic medications. No previous cases of MRONJ secondary to endotracheal intubation have been reported in the oral and maxillofacial surgery literature. PATIENT CONCERNS: This case report describes a patient on long-term oral bisphosphonate therapy who presented with a nonhealing ulcer and exposed bony island along her right mandibular torus after undergoing general anaesthesia. DIAGNOSIS: The lesion was diagnosed to be MRONJ secondary to pressure necrosis from postendotracheal intubation. These findings are suggested to be the result of poor control of the endotracheal tube while managing the airway. TREATMENT AND OUTCOMES: After treatment with antibiotics and mouth rinses, the necrotic bone spontaneously dislodged with complete mucosalisation of the exposed site within 2 weeks. TAKE-AWAY LESSONS: Given the severe impact of MRONJ, it is imperative to recognise and minimise all controllable risk factors associated with its development.
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spelling pubmed-95278272022-10-04 The Role of Endotracheal Tube in Medication-Related Osteonecrosis of the Jaw - A Case Report Niloy, Injamamul L. Burkes, Jason N. Ann Maxillofac Surg Case Report - Infections RATIONALE: Various traumatic risk factors have been correlated to the development of medication-related osteonecrosis of the jaw (MRONJ), with long-term use of antiresorptive or antiangiogenic medications. No previous cases of MRONJ secondary to endotracheal intubation have been reported in the oral and maxillofacial surgery literature. PATIENT CONCERNS: This case report describes a patient on long-term oral bisphosphonate therapy who presented with a nonhealing ulcer and exposed bony island along her right mandibular torus after undergoing general anaesthesia. DIAGNOSIS: The lesion was diagnosed to be MRONJ secondary to pressure necrosis from postendotracheal intubation. These findings are suggested to be the result of poor control of the endotracheal tube while managing the airway. TREATMENT AND OUTCOMES: After treatment with antibiotics and mouth rinses, the necrotic bone spontaneously dislodged with complete mucosalisation of the exposed site within 2 weeks. TAKE-AWAY LESSONS: Given the severe impact of MRONJ, it is imperative to recognise and minimise all controllable risk factors associated with its development. Wolters Kluwer - Medknow 2022 2022-08-16 /pmc/articles/PMC9527827/ /pubmed/36199473 http://dx.doi.org/10.4103/ams.ams_300_21 Text en Copyright: © 2022 Annals of Maxillofacial Surgery https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report - Infections
Niloy, Injamamul L.
Burkes, Jason N.
The Role of Endotracheal Tube in Medication-Related Osteonecrosis of the Jaw - A Case Report
title The Role of Endotracheal Tube in Medication-Related Osteonecrosis of the Jaw - A Case Report
title_full The Role of Endotracheal Tube in Medication-Related Osteonecrosis of the Jaw - A Case Report
title_fullStr The Role of Endotracheal Tube in Medication-Related Osteonecrosis of the Jaw - A Case Report
title_full_unstemmed The Role of Endotracheal Tube in Medication-Related Osteonecrosis of the Jaw - A Case Report
title_short The Role of Endotracheal Tube in Medication-Related Osteonecrosis of the Jaw - A Case Report
title_sort role of endotracheal tube in medication-related osteonecrosis of the jaw - a case report
topic Case Report - Infections
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527827/
https://www.ncbi.nlm.nih.gov/pubmed/36199473
http://dx.doi.org/10.4103/ams.ams_300_21
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