Regulation of cardiomyocyte adhesion and mechanosignalling through distinct nanoscale behaviour of integrin ligands mimicking healthy or fibrotic extracellular matrix

The stiffness of the cardiovascular environment changes during ageing and in disease and contributes to disease incidence and progression. Changing collagen expression and cross-linking regulate the rigidity of the cardiac extracellular matrix (ECM). Additionally, basal lamina glycoproteins, especia...

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Detalles Bibliográficos
Autores principales: Hawkes, William, Marhuenda, Emilie, Reynolds, Paul, O'Neill, Caoimhe, Pandey, Pragati, Samuel Wilson, Darren Graham, Freeley, Mark, Huang, Da, Hu, Junquiang, Gondarenko, Sasha, Hone, James, Gadegaard, Nikolaj, Palma, Matteo, Iskratsch, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527911/
https://www.ncbi.nlm.nih.gov/pubmed/36189804
http://dx.doi.org/10.1098/rstb.2022.0021

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