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Effects of altered cellular ultrastructure on energy metabolism in diabetic cardiomyopathy: an in silico study
Diabetic cardiomyopathy is a leading cause of heart failure in diabetes. At the cellular level, diabetic cardiomyopathy leads to altered mitochondrial energy metabolism and cardiomyocyte ultrastructure. We combined electron microscopy (EM) and computational modelling to understand the impact of diab...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527921/ https://www.ncbi.nlm.nih.gov/pubmed/36189807 http://dx.doi.org/10.1098/rstb.2021.0323 |