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Stability of scRNA-Seq Analysis Workflows is Susceptible to Preprocessing and is Mitigated by Regularized or Supervised Approaches

BACKGROUND: Statistical methods developed to address various questions in single-cell datasets show increased variability to different parameter regimes. In order to delineate further the robustness of commonly utilized methods for single-cell RNA-Seq, we aimed to comprehensively review scRNA-Seq an...

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Detalles Bibliográficos
Autores principales: Durmaz, Arda, Scott, Jacob G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527995/
https://www.ncbi.nlm.nih.gov/pubmed/36199555
http://dx.doi.org/10.1177/11769343221123050

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