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ACSL3 regulates lipid droplet biogenesis and ferroptosis sensitivity in clear cell renal cell carcinoma

BACKGROUND: Clear cell renal cell carcinoma (ccRCC), the predominant subtype of kidney cancer, possesses characteristic alterations to multiple metabolic pathways, including the accumulation of cytosolic lipid droplets. However, the pathways that drive lipid droplet accumulation in ccRCC cells and t...

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Detalles Bibliográficos
Autores principales:	Klasson, Timothy D., LaGory, Edward L., Zhao, Hongjuan, Huynh, Star K., Papandreou, Ioanna, Moon, Eui Jung, Giaccia, Amato J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528056/ https://www.ncbi.nlm.nih.gov/pubmed/36192773 http://dx.doi.org/10.1186/s40170-022-00290-z

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