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Non-infectious sternal dehiscence after coronary artery bypass surgery

INTRODUCTION: Non-infectious sternal dehiscence (NISD) is a known complication following coronary artery bypass grafting (CABG), with previous studies estimating an incidence of 0.4–1% of surgeries. We aimed to study the incidence of NISD together with short- and long-term outcomes in a whole-nation...

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Autores principales: Silverborn, Martin, Heitmann, Leon Arnar, Sveinsdottir, Nanna, Rögnvaldsson, Sigurjon, Kristjansson, Tomas Thor, Gudbjartsson, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528060/
https://www.ncbi.nlm.nih.gov/pubmed/36192764
http://dx.doi.org/10.1186/s13019-022-02015-1
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author Silverborn, Martin
Heitmann, Leon Arnar
Sveinsdottir, Nanna
Rögnvaldsson, Sigurjon
Kristjansson, Tomas Thor
Gudbjartsson, Tomas
author_facet Silverborn, Martin
Heitmann, Leon Arnar
Sveinsdottir, Nanna
Rögnvaldsson, Sigurjon
Kristjansson, Tomas Thor
Gudbjartsson, Tomas
author_sort Silverborn, Martin
collection PubMed
description INTRODUCTION: Non-infectious sternal dehiscence (NISD) is a known complication following coronary artery bypass grafting (CABG), with previous studies estimating an incidence of 0.4–1% of surgeries. We aimed to study the incidence of NISD together with short- and long-term outcomes in a whole-nation cohort of patients. MATERIALS AND METHODS: A retrospective study on consecutive CABG patients diagnosed with NISD at Landspitali from 2001 to 2020. Patients diagnosed with infectious mediastinitis (n = 20) were excluded. NISD patients were compared to patients with an intact sternum regarding patient demographics, cardiovascular risk factors, intra- and postoperative data, and estimated overall survival. The median follow-up was 9.5 years. RESULTS: Twenty out of 2280 eligible patients (0.88%) developed NISD, and the incidence did not change over the study period (p = 0.98). The median time of diagnosis was 12 days postoperatively (range, 4–240). All patients were re-operated using a Robicsek-rewiring technique, with two cases requiring a titanium plate for fixation. Patients with NISD were older, had a higher BMI and EuroSCORE II, lower LVEF, and more often had a history of COPD, MI, and diabetes compared to those without NISD. Length of stay was extended by 15 days for NISD patients, but short and long-term survival was not statistically different between the groups. CONCLUSIONS: The incidence of NISD was low and in line with previous studies. Although the length of hospital stay was extended, both short- and long-term survival of NISD patients was not significantly different from patients with an intact sternum.
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spelling pubmed-95280602022-10-04 Non-infectious sternal dehiscence after coronary artery bypass surgery Silverborn, Martin Heitmann, Leon Arnar Sveinsdottir, Nanna Rögnvaldsson, Sigurjon Kristjansson, Tomas Thor Gudbjartsson, Tomas J Cardiothorac Surg Research INTRODUCTION: Non-infectious sternal dehiscence (NISD) is a known complication following coronary artery bypass grafting (CABG), with previous studies estimating an incidence of 0.4–1% of surgeries. We aimed to study the incidence of NISD together with short- and long-term outcomes in a whole-nation cohort of patients. MATERIALS AND METHODS: A retrospective study on consecutive CABG patients diagnosed with NISD at Landspitali from 2001 to 2020. Patients diagnosed with infectious mediastinitis (n = 20) were excluded. NISD patients were compared to patients with an intact sternum regarding patient demographics, cardiovascular risk factors, intra- and postoperative data, and estimated overall survival. The median follow-up was 9.5 years. RESULTS: Twenty out of 2280 eligible patients (0.88%) developed NISD, and the incidence did not change over the study period (p = 0.98). The median time of diagnosis was 12 days postoperatively (range, 4–240). All patients were re-operated using a Robicsek-rewiring technique, with two cases requiring a titanium plate for fixation. Patients with NISD were older, had a higher BMI and EuroSCORE II, lower LVEF, and more often had a history of COPD, MI, and diabetes compared to those without NISD. Length of stay was extended by 15 days for NISD patients, but short and long-term survival was not statistically different between the groups. CONCLUSIONS: The incidence of NISD was low and in line with previous studies. Although the length of hospital stay was extended, both short- and long-term survival of NISD patients was not significantly different from patients with an intact sternum. BioMed Central 2022-10-03 /pmc/articles/PMC9528060/ /pubmed/36192764 http://dx.doi.org/10.1186/s13019-022-02015-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Silverborn, Martin
Heitmann, Leon Arnar
Sveinsdottir, Nanna
Rögnvaldsson, Sigurjon
Kristjansson, Tomas Thor
Gudbjartsson, Tomas
Non-infectious sternal dehiscence after coronary artery bypass surgery
title Non-infectious sternal dehiscence after coronary artery bypass surgery
title_full Non-infectious sternal dehiscence after coronary artery bypass surgery
title_fullStr Non-infectious sternal dehiscence after coronary artery bypass surgery
title_full_unstemmed Non-infectious sternal dehiscence after coronary artery bypass surgery
title_short Non-infectious sternal dehiscence after coronary artery bypass surgery
title_sort non-infectious sternal dehiscence after coronary artery bypass surgery
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528060/
https://www.ncbi.nlm.nih.gov/pubmed/36192764
http://dx.doi.org/10.1186/s13019-022-02015-1
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