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Capparis spinosa improves non-alcoholic steatohepatitis through down-regulating SREBP-1c and a PPARα-independent pathway in high-fat diet-fed rats

OBJECTIVE: Non-alcoholic steatohepatitis (NASH) has become a global medical problem. Currently, there is no approved pharmacologic treatment for this condition. Previous studies have suggested that in the pathogenesis of this disease, regulatory pathways associated with de novo lipogenesis and β-oxi...

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Detalles Bibliográficos
Autores principales: Akbari, Rasoul, Yaghooti, Hamid, Jalali, Mohammad Taha, Khorsandi, Laya Sadat, Mohammadtaghvaei, Narges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528135/
https://www.ncbi.nlm.nih.gov/pubmed/36192786
http://dx.doi.org/10.1186/s13104-022-06205-x

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