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Loss of endothelial EMCN drives tumor lung metastasis through the premetastatic niche

BACKGROUND: Metastasis is the primary cause of cancer-related mortality. Metastasis involves a complex multistep process during which individual tumor cells spread primarily through destruction of the endothelial barrier, entering the circulatory system to colonize distant organs. However, the role...

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Detalles Bibliográficos
Autores principales: Zhang, Guoxin, Li, Mengyuan, Zhou, Dandan, Yang, Xingjiu, Zhang, Wenlong, Gao, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528146/
https://www.ncbi.nlm.nih.gov/pubmed/36184589
http://dx.doi.org/10.1186/s12967-022-03649-4