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Loss of endothelial EMCN drives tumor lung metastasis through the premetastatic niche
BACKGROUND: Metastasis is the primary cause of cancer-related mortality. Metastasis involves a complex multistep process during which individual tumor cells spread primarily through destruction of the endothelial barrier, entering the circulatory system to colonize distant organs. However, the role...
Autores principales: | Zhang, Guoxin, Li, Mengyuan, Zhou, Dandan, Yang, Xingjiu, Zhang, Wenlong, Gao, Ran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528146/ https://www.ncbi.nlm.nih.gov/pubmed/36184589 http://dx.doi.org/10.1186/s12967-022-03649-4 |
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