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CD4(+) T-cell cooperation promoted pathogenic function of activated naïve B cells of patients with SLE

OBJECTIVE: To explore cooperation between activated naïve (aNAV) B cells and CD4(+) T cells in the pathogenesis of SLE through autoantibody production, T-cell differentiation and inflammatory cytokine secretion. METHODS: Peripheral blood mononuclear cell samples were obtained from 31 patients with S...

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Detalles Bibliográficos
Autores principales: Wangriatisak, Kittikorn, Kochayoo, Piyawan, Thawornpan, Pongsakorn, Leepiyasakulchai, Chaniya, Suangtamai, Thanitta, Ngamjanyaporn, Pintip, Khowawisetsut, Ladawan, Khaenam, Prasong, Pisitkun, Prapaporn, Chootong, Patchanee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528597/
https://www.ncbi.nlm.nih.gov/pubmed/36180106
http://dx.doi.org/10.1136/lupus-2022-000739