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Sirt6 deficiency contributes to mitochondrial fission and oxidative damage in podocytes via ROCK1‐Drp1 signalling pathway

OBJECTIVES: Increasing evidence suggests that mitochondrial dysfunction is the key driver of angiotensin II (Ang II)‐induced kidney injury. This study was designed to investigate whether Sirtuin 6 (Sirt6) could affect Ang II‐induced mitochondrial damage and the potential mechanisms. MATERIALS AND ME...

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Detalles Bibliográficos
Autores principales:	Chen, Zhaowei, Liang, Wei, Hu, Jijia, Zhu, Zijing, Feng, Jun, Ma, Yiqiong, Yang, Qian, Ding, Guohua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528772/ https://www.ncbi.nlm.nih.gov/pubmed/35842903 http://dx.doi.org/10.1111/cpr.13296

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