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Ulcerated Tophaceous Gout

Gout is a disease that occurs in response to the presence of monosodium urate (MSU) crystals typically within joints. Patients with gout may develop a chronic deposition of monosodium urate crystals within or around joints, cartilage, tendons, peri-articular, and subcutaneous tissue. This condition...

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Detalles Bibliográficos
Autores principales: Zahoor, Hovra, Patel, Ronak, El-bahri, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528853/
https://www.ncbi.nlm.nih.gov/pubmed/36204027
http://dx.doi.org/10.7759/cureus.28729
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author Zahoor, Hovra
Patel, Ronak
El-bahri, Jessica
author_facet Zahoor, Hovra
Patel, Ronak
El-bahri, Jessica
author_sort Zahoor, Hovra
collection PubMed
description Gout is a disease that occurs in response to the presence of monosodium urate (MSU) crystals typically within joints. Patients with gout may develop a chronic deposition of monosodium urate crystals within or around joints, cartilage, tendons, peri-articular, and subcutaneous tissue. This condition is termed “tophaceous gout.” Ulceration of the skin by tophi is very uncommon. Literature regarding the clinical course and the management of ulcerated tophi is limited and, therefore, treatment options are not well established. We hereby present a case of a 46-year-old male who presented to our facility with poorly controlled polyarticular tophaceous gout complicated by ulcerated tophi. Our hope is to contribute to the limited knowledge of this rare disease process and to contribute toward formulating the best management approach.
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spelling pubmed-95288532022-10-05 Ulcerated Tophaceous Gout Zahoor, Hovra Patel, Ronak El-bahri, Jessica Cureus Internal Medicine Gout is a disease that occurs in response to the presence of monosodium urate (MSU) crystals typically within joints. Patients with gout may develop a chronic deposition of monosodium urate crystals within or around joints, cartilage, tendons, peri-articular, and subcutaneous tissue. This condition is termed “tophaceous gout.” Ulceration of the skin by tophi is very uncommon. Literature regarding the clinical course and the management of ulcerated tophi is limited and, therefore, treatment options are not well established. We hereby present a case of a 46-year-old male who presented to our facility with poorly controlled polyarticular tophaceous gout complicated by ulcerated tophi. Our hope is to contribute to the limited knowledge of this rare disease process and to contribute toward formulating the best management approach. Cureus 2022-09-03 /pmc/articles/PMC9528853/ /pubmed/36204027 http://dx.doi.org/10.7759/cureus.28729 Text en Copyright © 2022, Zahoor et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Zahoor, Hovra
Patel, Ronak
El-bahri, Jessica
Ulcerated Tophaceous Gout
title Ulcerated Tophaceous Gout
title_full Ulcerated Tophaceous Gout
title_fullStr Ulcerated Tophaceous Gout
title_full_unstemmed Ulcerated Tophaceous Gout
title_short Ulcerated Tophaceous Gout
title_sort ulcerated tophaceous gout
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528853/
https://www.ncbi.nlm.nih.gov/pubmed/36204027
http://dx.doi.org/10.7759/cureus.28729
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