Spontaneous Escherichia coli Meningitis and Brain Abscess in an Immunocompetent Adult

Escherichia coli is widely known to be a common cause of gram-negative bacterial meningitis in neonates and infants but is a rare cause of central nervous system infection in adults. Risk factors for E. coli meningitis (e.g., penetrating head trauma or neurosurgery) have been broadly discussed in the literature. Here, we describe a case of spontaneous E. coli meningitis with multiple enhancing brain lesions and liver abscess in an immunocompetent adult that presented as generalized weakness.