IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern

Monoclonal antibodies are a promising approach to treat COVID-19, however the emergence of SARS-CoV-2 variants has challenged the efficacy and future of these therapies. Antibody cocktails are being employed to mitigate these challenges, but neutralization escape remains a major challenge and altern...

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Detalles Bibliográficos
Autores principales: Chang, Matthew R., Tomasovic, Luke, Kuzmina, Natalia A., Ronk, Adam J., Byrne, Patrick O., Johnson, Rebecca, Storm, Nadia, Olmedillas, Eduardo, Hou, Yixuan J., Schäfer, Alexandra, Leist, Sarah R., Tse, Longping V., Ke, Hanzhong, Coherd, Christian, Nguyen, Katrina, Kamkaew, Maliwan, Honko, Anna, Zhu, Quan, Alter, Galit, Saphire, Erica Ollmann, McLellan, Jason S., Griffiths, Anthony, Baric, Ralph S., Bukreyev, Alexander, Marasco, Wayne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528872/
https://www.ncbi.nlm.nih.gov/pubmed/36192374
http://dx.doi.org/10.1038/s41467-022-33030-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528872/
https://www.ncbi.nlm.nih.gov/pubmed/36192374
http://dx.doi.org/10.1038/s41467-022-33030-4

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