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Widespread association of the Argonaute protein AGO2 with meiotic chromatin suggests a distinct nuclear function in mammalian male reproduction

Argonaute 2 (AGO2) is a ubiquitously expressed protein critical for regulation of mRNA translation and vital to animal development. AGO2 protein is found in both cytoplasmic and nuclear compartments, and although its cytoplasmic role is well studied, the biological relevance of nuclear AGO2 is uncle...

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Detalles Bibliográficos
Autores principales: Griffin, Kimberly N., Walters, Benjamin William, Li, Haixin, Wang, Huafeng, Biancon, Giulia, Tebaldi, Toma, Kaya, Carolyn B., Kanyo, Jean, Lam, TuKiet T., Cox, Andy L., Halene, Stephanie, Chung, Jean-Ju, Lesch, Bluma J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528986/
https://www.ncbi.nlm.nih.gov/pubmed/36109149
http://dx.doi.org/10.1101/gr.276578.122