Learning probabilistic protein–DNA recognition codes from DNA-binding specificities using structural mappings

Knowledge of how proteins interact with DNA is essential for understanding gene regulation. Although DNA-binding specificities for thousands of transcription factors (TFs) have been determined, the specific amino acid–base interactions comprising their structural interfaces are largely unknown. This...

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Detalles Bibliográficos
Autores principales: Wetzel, Joshua L., Zhang, Kaiqian, Singh, Mona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
RECOMB 2022 Special/Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528988/
https://www.ncbi.nlm.nih.gov/pubmed/36123148
http://dx.doi.org/10.1101/gr.276606.122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528988/
https://www.ncbi.nlm.nih.gov/pubmed/36123148
http://dx.doi.org/10.1101/gr.276606.122

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