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Every day mitral valve reconstruction: What has changed over the last 15 years?
OBJECTIVE: Mitral valve reconstruction (MVR) is one of the cardiosurgical procedures which cannot be substituted by any intervention owing to the quality of the quasi-anatomical, physiological repair. However, technique and strategies have changed over the years. We looked at procedural characterist...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529113/ https://www.ncbi.nlm.nih.gov/pubmed/36191013 http://dx.doi.org/10.1371/journal.pone.0269537 |
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author | Motazedian, Farnoosh Ostovar, Roya Hartrumpf, Martin Schröter, Filip Albes, Johannes M. |
author_facet | Motazedian, Farnoosh Ostovar, Roya Hartrumpf, Martin Schröter, Filip Albes, Johannes M. |
author_sort | Motazedian, Farnoosh |
collection | PubMed |
description | OBJECTIVE: Mitral valve reconstruction (MVR) is one of the cardiosurgical procedures which cannot be substituted by any intervention owing to the quality of the quasi-anatomical, physiological repair. However, technique and strategies have changed over the years. We looked at procedural characteristics and outcome in an all-comer, non-selected cohort of patients. METHODS: 738 out of 1.977 patients were retrospectively analyzed receiving MVR with and without concomitant procedures. The cohort was divided into three periods. P1: 2004–2009 (134 pts.); P2: 2010–2014 (294 pts.), and P3: 2015–2019 (310 pts.). RESULTS: Early mortality increased from P1 to P2 and decreased from P2 to P3 (9% P1, 13% P2, 10% P3). All patients received an annuloplasty-ring. In P1 resection measures dominated. In P3 artificial chordae were dominant. Age, BMI, and risk scores correlated with early mortality. Survival rates were 66% (5-years), 55% (10-years), 44% (15-years) in P1, 63% (5-years), 50% (10-years) in P2, and 80% (5-years) in P3. Odds ratio for reduced long-term survival were concomitant venous only bypass surgery (10-years 2,701, p = 0.026). 10-year survival was positively influenced by isolated MVR (0.246, p = 0.001), concomitant isolated arterial bypass (IMA) (0.153, p = 0.051), posterior leaflet measure (0.178, p<0.001), and use of artificial chordae (5-years 0.235, p<0.001). CONCLUSION: Indication for ring implantation remained mandatory while preference changed alongside improved designs. Procedural characteristics changed from mainly resection maneuvers to predominant use of artificial chordae. Long-term results were negatively influenced by co-morbidities and positively influenced by posterior leaflet repair and artificial chordae. MVR underwent a qualitative evolution and remains a valuable cardiosurgical procedure. |
format | Online Article Text |
id | pubmed-9529113 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-95291132022-10-04 Every day mitral valve reconstruction: What has changed over the last 15 years? Motazedian, Farnoosh Ostovar, Roya Hartrumpf, Martin Schröter, Filip Albes, Johannes M. PLoS One Research Article OBJECTIVE: Mitral valve reconstruction (MVR) is one of the cardiosurgical procedures which cannot be substituted by any intervention owing to the quality of the quasi-anatomical, physiological repair. However, technique and strategies have changed over the years. We looked at procedural characteristics and outcome in an all-comer, non-selected cohort of patients. METHODS: 738 out of 1.977 patients were retrospectively analyzed receiving MVR with and without concomitant procedures. The cohort was divided into three periods. P1: 2004–2009 (134 pts.); P2: 2010–2014 (294 pts.), and P3: 2015–2019 (310 pts.). RESULTS: Early mortality increased from P1 to P2 and decreased from P2 to P3 (9% P1, 13% P2, 10% P3). All patients received an annuloplasty-ring. In P1 resection measures dominated. In P3 artificial chordae were dominant. Age, BMI, and risk scores correlated with early mortality. Survival rates were 66% (5-years), 55% (10-years), 44% (15-years) in P1, 63% (5-years), 50% (10-years) in P2, and 80% (5-years) in P3. Odds ratio for reduced long-term survival were concomitant venous only bypass surgery (10-years 2,701, p = 0.026). 10-year survival was positively influenced by isolated MVR (0.246, p = 0.001), concomitant isolated arterial bypass (IMA) (0.153, p = 0.051), posterior leaflet measure (0.178, p<0.001), and use of artificial chordae (5-years 0.235, p<0.001). CONCLUSION: Indication for ring implantation remained mandatory while preference changed alongside improved designs. Procedural characteristics changed from mainly resection maneuvers to predominant use of artificial chordae. Long-term results were negatively influenced by co-morbidities and positively influenced by posterior leaflet repair and artificial chordae. MVR underwent a qualitative evolution and remains a valuable cardiosurgical procedure. Public Library of Science 2022-10-03 /pmc/articles/PMC9529113/ /pubmed/36191013 http://dx.doi.org/10.1371/journal.pone.0269537 Text en © 2022 Motazedian et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Motazedian, Farnoosh Ostovar, Roya Hartrumpf, Martin Schröter, Filip Albes, Johannes M. Every day mitral valve reconstruction: What has changed over the last 15 years? |
title | Every day mitral valve reconstruction: What has changed over the last 15 years? |
title_full | Every day mitral valve reconstruction: What has changed over the last 15 years? |
title_fullStr | Every day mitral valve reconstruction: What has changed over the last 15 years? |
title_full_unstemmed | Every day mitral valve reconstruction: What has changed over the last 15 years? |
title_short | Every day mitral valve reconstruction: What has changed over the last 15 years? |
title_sort | every day mitral valve reconstruction: what has changed over the last 15 years? |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529113/ https://www.ncbi.nlm.nih.gov/pubmed/36191013 http://dx.doi.org/10.1371/journal.pone.0269537 |
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