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Every day mitral valve reconstruction: What has changed over the last 15 years?

OBJECTIVE: Mitral valve reconstruction (MVR) is one of the cardiosurgical procedures which cannot be substituted by any intervention owing to the quality of the quasi-anatomical, physiological repair. However, technique and strategies have changed over the years. We looked at procedural characterist...

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Autores principales: Motazedian, Farnoosh, Ostovar, Roya, Hartrumpf, Martin, Schröter, Filip, Albes, Johannes M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529113/
https://www.ncbi.nlm.nih.gov/pubmed/36191013
http://dx.doi.org/10.1371/journal.pone.0269537
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author Motazedian, Farnoosh
Ostovar, Roya
Hartrumpf, Martin
Schröter, Filip
Albes, Johannes M.
author_facet Motazedian, Farnoosh
Ostovar, Roya
Hartrumpf, Martin
Schröter, Filip
Albes, Johannes M.
author_sort Motazedian, Farnoosh
collection PubMed
description OBJECTIVE: Mitral valve reconstruction (MVR) is one of the cardiosurgical procedures which cannot be substituted by any intervention owing to the quality of the quasi-anatomical, physiological repair. However, technique and strategies have changed over the years. We looked at procedural characteristics and outcome in an all-comer, non-selected cohort of patients. METHODS: 738 out of 1.977 patients were retrospectively analyzed receiving MVR with and without concomitant procedures. The cohort was divided into three periods. P1: 2004–2009 (134 pts.); P2: 2010–2014 (294 pts.), and P3: 2015–2019 (310 pts.). RESULTS: Early mortality increased from P1 to P2 and decreased from P2 to P3 (9% P1, 13% P2, 10% P3). All patients received an annuloplasty-ring. In P1 resection measures dominated. In P3 artificial chordae were dominant. Age, BMI, and risk scores correlated with early mortality. Survival rates were 66% (5-years), 55% (10-years), 44% (15-years) in P1, 63% (5-years), 50% (10-years) in P2, and 80% (5-years) in P3. Odds ratio for reduced long-term survival were concomitant venous only bypass surgery (10-years 2,701, p = 0.026). 10-year survival was positively influenced by isolated MVR (0.246, p = 0.001), concomitant isolated arterial bypass (IMA) (0.153, p = 0.051), posterior leaflet measure (0.178, p<0.001), and use of artificial chordae (5-years 0.235, p<0.001). CONCLUSION: Indication for ring implantation remained mandatory while preference changed alongside improved designs. Procedural characteristics changed from mainly resection maneuvers to predominant use of artificial chordae. Long-term results were negatively influenced by co-morbidities and positively influenced by posterior leaflet repair and artificial chordae. MVR underwent a qualitative evolution and remains a valuable cardiosurgical procedure.
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spelling pubmed-95291132022-10-04 Every day mitral valve reconstruction: What has changed over the last 15 years? Motazedian, Farnoosh Ostovar, Roya Hartrumpf, Martin Schröter, Filip Albes, Johannes M. PLoS One Research Article OBJECTIVE: Mitral valve reconstruction (MVR) is one of the cardiosurgical procedures which cannot be substituted by any intervention owing to the quality of the quasi-anatomical, physiological repair. However, technique and strategies have changed over the years. We looked at procedural characteristics and outcome in an all-comer, non-selected cohort of patients. METHODS: 738 out of 1.977 patients were retrospectively analyzed receiving MVR with and without concomitant procedures. The cohort was divided into three periods. P1: 2004–2009 (134 pts.); P2: 2010–2014 (294 pts.), and P3: 2015–2019 (310 pts.). RESULTS: Early mortality increased from P1 to P2 and decreased from P2 to P3 (9% P1, 13% P2, 10% P3). All patients received an annuloplasty-ring. In P1 resection measures dominated. In P3 artificial chordae were dominant. Age, BMI, and risk scores correlated with early mortality. Survival rates were 66% (5-years), 55% (10-years), 44% (15-years) in P1, 63% (5-years), 50% (10-years) in P2, and 80% (5-years) in P3. Odds ratio for reduced long-term survival were concomitant venous only bypass surgery (10-years 2,701, p = 0.026). 10-year survival was positively influenced by isolated MVR (0.246, p = 0.001), concomitant isolated arterial bypass (IMA) (0.153, p = 0.051), posterior leaflet measure (0.178, p<0.001), and use of artificial chordae (5-years 0.235, p<0.001). CONCLUSION: Indication for ring implantation remained mandatory while preference changed alongside improved designs. Procedural characteristics changed from mainly resection maneuvers to predominant use of artificial chordae. Long-term results were negatively influenced by co-morbidities and positively influenced by posterior leaflet repair and artificial chordae. MVR underwent a qualitative evolution and remains a valuable cardiosurgical procedure. Public Library of Science 2022-10-03 /pmc/articles/PMC9529113/ /pubmed/36191013 http://dx.doi.org/10.1371/journal.pone.0269537 Text en © 2022 Motazedian et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Motazedian, Farnoosh
Ostovar, Roya
Hartrumpf, Martin
Schröter, Filip
Albes, Johannes M.
Every day mitral valve reconstruction: What has changed over the last 15 years?
title Every day mitral valve reconstruction: What has changed over the last 15 years?
title_full Every day mitral valve reconstruction: What has changed over the last 15 years?
title_fullStr Every day mitral valve reconstruction: What has changed over the last 15 years?
title_full_unstemmed Every day mitral valve reconstruction: What has changed over the last 15 years?
title_short Every day mitral valve reconstruction: What has changed over the last 15 years?
title_sort every day mitral valve reconstruction: what has changed over the last 15 years?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529113/
https://www.ncbi.nlm.nih.gov/pubmed/36191013
http://dx.doi.org/10.1371/journal.pone.0269537
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