Doxorubicin induces prolonged DNA damage signal in cells overexpressing DEK isoform-2

DEK has a short isoform (DEK isoform-2; DEK2) that lacks amino acid residues between 49–82. The full-length DEK (DEK isoform-1; DEK1) is ubiquitously expressed and plays a role in different cellular processes but whether DEK2 is involved in these processes remains elusive. We stably overexpressed DE...

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Detalles Bibliográficos
Autores principales: Özçelik, Emrah, Kalaycı, Ahmet, Çelik, Büşra, Avcı, Açelya, Akyol, Hasan, Kılıç, İrfan Baki, Güzel, Türkan, Çetin, Metin, Öztürk, Merve Tuzlakoğlu, Çalışkaner, Zihni Onur, Tombaz, Melike, Yoleri, Dilan, Konu, Özlen, Kandilci, Ayten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529144/
https://www.ncbi.nlm.nih.gov/pubmed/36190960
http://dx.doi.org/10.1371/journal.pone.0275476

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