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The lonidamine derivative H2-gamendazole reduces cyst formation in polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) is a debilitating renal neoplastic disorder with limited treatment options. It is characterized by the formation of large fluid-filled cysts that develop from kidney tubules through abnormal cell proliferation and cyst-filling fluid secretion driv...

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Detalles Bibliográficos
Autores principales: Sundar, Shirin V., Zhou, Julie Xia, Magenheimer, Brenda S., Reif, Gail A., Wallace, Darren P., Georg, Gunda I., Jakkaraj, Sudhakar R., Tash, Joseph S., Yu, Alan S.L., Li, Xiaogang, Calvet, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529276/
https://www.ncbi.nlm.nih.gov/pubmed/35979967
http://dx.doi.org/10.1152/ajprenal.00095.2022