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The lonidamine derivative H2-gamendazole reduces cyst formation in polycystic kidney disease
Autosomal dominant polycystic kidney disease (ADPKD) is a debilitating renal neoplastic disorder with limited treatment options. It is characterized by the formation of large fluid-filled cysts that develop from kidney tubules through abnormal cell proliferation and cyst-filling fluid secretion driv...
Autores principales: | Sundar, Shirin V., Zhou, Julie Xia, Magenheimer, Brenda S., Reif, Gail A., Wallace, Darren P., Georg, Gunda I., Jakkaraj, Sudhakar R., Tash, Joseph S., Yu, Alan S.L., Li, Xiaogang, Calvet, James P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529276/ https://www.ncbi.nlm.nih.gov/pubmed/35979967 http://dx.doi.org/10.1152/ajprenal.00095.2022 |
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