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Reconstitution of the SARS-CoV-2 ribonucleosome provides insights into genomic RNA packaging and regulation by phosphorylation

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The nucleocapsid (N) protein of severe acute respiratory syndrome coronavirus 2 is responsible for compaction of the ∼30-kb RNA genome in the ∼90-nm virion. Previous studies suggest that each virion contains 35 to 40 viral ribonucleoprotein (vRNP) complexes, or ribonucleosomes, arrayed along the gen...

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Detalles Bibliográficos
Autores principales:	Carlson, Christopher R., Adly, Armin N., Bi, Maxine, Howard, Conor J., Frost, Adam, Cheng, Yifan, Morgan, David O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529352/ https://www.ncbi.nlm.nih.gov/pubmed/36202211 http://dx.doi.org/10.1016/j.jbc.2022.102560

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