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Optimization, Characterization, and Anticancer Potential of Silver Nanoparticles Biosynthesized Using Olea europaea

Green synthesis has attracted significant attention as an eco-friendly, low-cost, energy-efficient, and non-toxic method for preparing silver nanoparticles (AgNPs) for cancer therapy. This study optimized the green synthesis of AgNPs using Olea europaea extracts and evaluated their anticancer potent...

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Detalles Bibliográficos
Autores principales: Felimban, Afnan I., Alharbi, Njud S., Alsubhi, Nehad S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529486/
https://www.ncbi.nlm.nih.gov/pubmed/36199851
http://dx.doi.org/10.1155/2022/6859637
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author Felimban, Afnan I.
Alharbi, Njud S.
Alsubhi, Nehad S.
author_facet Felimban, Afnan I.
Alharbi, Njud S.
Alsubhi, Nehad S.
author_sort Felimban, Afnan I.
collection PubMed
description Green synthesis has attracted significant attention as an eco-friendly, low-cost, energy-efficient, and non-toxic method for preparing silver nanoparticles (AgNPs) for cancer therapy. This study optimized the green synthesis of AgNPs using Olea europaea extracts and evaluated their anticancer potential. The biosynthesized AgNPs were characterized using various methods, showing stable AgNPs with a desirable morphology and high yield, improving the properties of AgNPs for various medicinal applications. The biosynthesized AgNPs were predominantly spherical, with small sizes ranging from 13 to 21 nm and highly stable at −23 and −24 mV. The findings of this study suggest that green-synthesized AgNPs using Olea europaea and sunlight possess significant anticancer activity against cancer cells in vitro. Further investigation of green synthesis would help to form high-quality AgNPs that have promising potential in treating disease and fighting undesirable pathogens.
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spelling pubmed-95294862022-10-04 Optimization, Characterization, and Anticancer Potential of Silver Nanoparticles Biosynthesized Using Olea europaea Felimban, Afnan I. Alharbi, Njud S. Alsubhi, Nehad S. Int J Biomater Research Article Green synthesis has attracted significant attention as an eco-friendly, low-cost, energy-efficient, and non-toxic method for preparing silver nanoparticles (AgNPs) for cancer therapy. This study optimized the green synthesis of AgNPs using Olea europaea extracts and evaluated their anticancer potential. The biosynthesized AgNPs were characterized using various methods, showing stable AgNPs with a desirable morphology and high yield, improving the properties of AgNPs for various medicinal applications. The biosynthesized AgNPs were predominantly spherical, with small sizes ranging from 13 to 21 nm and highly stable at −23 and −24 mV. The findings of this study suggest that green-synthesized AgNPs using Olea europaea and sunlight possess significant anticancer activity against cancer cells in vitro. Further investigation of green synthesis would help to form high-quality AgNPs that have promising potential in treating disease and fighting undesirable pathogens. Hindawi 2022-09-26 /pmc/articles/PMC9529486/ /pubmed/36199851 http://dx.doi.org/10.1155/2022/6859637 Text en Copyright © 2022 Afnan I. Felimban et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Felimban, Afnan I.
Alharbi, Njud S.
Alsubhi, Nehad S.
Optimization, Characterization, and Anticancer Potential of Silver Nanoparticles Biosynthesized Using Olea europaea
title Optimization, Characterization, and Anticancer Potential of Silver Nanoparticles Biosynthesized Using Olea europaea
title_full Optimization, Characterization, and Anticancer Potential of Silver Nanoparticles Biosynthesized Using Olea europaea
title_fullStr Optimization, Characterization, and Anticancer Potential of Silver Nanoparticles Biosynthesized Using Olea europaea
title_full_unstemmed Optimization, Characterization, and Anticancer Potential of Silver Nanoparticles Biosynthesized Using Olea europaea
title_short Optimization, Characterization, and Anticancer Potential of Silver Nanoparticles Biosynthesized Using Olea europaea
title_sort optimization, characterization, and anticancer potential of silver nanoparticles biosynthesized using olea europaea
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529486/
https://www.ncbi.nlm.nih.gov/pubmed/36199851
http://dx.doi.org/10.1155/2022/6859637
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