A software tool for both the maximum tolerated dose and the optimal biological dose finding trials in early phase designs

BACKGROUND: Phase I and/or I/II oncology trials are conducted to find the maximum tolerated dose (MTD) and/or optimal biological dose (OBD) of a new drug or treatment. In these trials, for cytotoxic agents, the primary aim of the single-agent or drug-combination is to find the MTD with a certain tar...

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Detalles Bibliográficos
Autores principales: Li, Chen, Sun, Hongying, Cheng, Cheng, Tang, Li, Pan, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529556/
https://www.ncbi.nlm.nih.gov/pubmed/36203850
http://dx.doi.org/10.1016/j.conctc.2022.100990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529556/
https://www.ncbi.nlm.nih.gov/pubmed/36203850
http://dx.doi.org/10.1016/j.conctc.2022.100990

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