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Pathological significance and classification of endolymphatic hydrops in otological disorders

We summarize the presence of endolymphatic hydrops (EH) in otological disorders evaluated with magnetic resonance imaging (MRI) of temporal bones, and propose a classification of EH based on its pathological significance. A search of the literature published in English-language journals was performe...

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Autores principales: Sone, Michihiko, Yoshida, Tadao, Sugimoto, Satofumi, Kobayashi, Masumi, Teranishi, Masaaki, Naganawa, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nagoya University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529623/
https://www.ncbi.nlm.nih.gov/pubmed/36237884
http://dx.doi.org/10.18999/nagjms.84.3.497
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author Sone, Michihiko
Yoshida, Tadao
Sugimoto, Satofumi
Kobayashi, Masumi
Teranishi, Masaaki
Naganawa, Shinji
author_facet Sone, Michihiko
Yoshida, Tadao
Sugimoto, Satofumi
Kobayashi, Masumi
Teranishi, Masaaki
Naganawa, Shinji
author_sort Sone, Michihiko
collection PubMed
description We summarize the presence of endolymphatic hydrops (EH) in otological disorders evaluated with magnetic resonance imaging (MRI) of temporal bones, and propose a classification of EH based on its pathological significance. A search of the literature published in English-language journals was performed using electronic databases, especially focusing on EH-related otological disorders. Clinical articles that contained the terms EH and contrast-MRI published from 2007 to the present, with relevant human temporal bone studies, were included. The following three main points are discussed based on the results in the relevant articles: i) otological disorders that present EH, ii) current grading for evaluation of EH on MRI, and iii) a proposed classification of EH based on its pathological significance. MRI evaluation revealed that EH exists extensively not only in ears with typical Meniere’s disease (MD), but also in those with various other otological disorders. The etiological classification of EH helps to summarize ideas for determining the pathophysiology of otological disorders, while a therapeutic classification provides clues to their management. MRI evaluations of EH have led to breakthroughs in investigations of EH in otological disorders. Precise grading for evaluation and clarification of EH on MRI based on its pathological significance could provide keys to elucidating the pathophysiology of EH-related otological disorders.
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spelling pubmed-95296232022-10-12 Pathological significance and classification of endolymphatic hydrops in otological disorders Sone, Michihiko Yoshida, Tadao Sugimoto, Satofumi Kobayashi, Masumi Teranishi, Masaaki Naganawa, Shinji Nagoya J Med Sci Review Article We summarize the presence of endolymphatic hydrops (EH) in otological disorders evaluated with magnetic resonance imaging (MRI) of temporal bones, and propose a classification of EH based on its pathological significance. A search of the literature published in English-language journals was performed using electronic databases, especially focusing on EH-related otological disorders. Clinical articles that contained the terms EH and contrast-MRI published from 2007 to the present, with relevant human temporal bone studies, were included. The following three main points are discussed based on the results in the relevant articles: i) otological disorders that present EH, ii) current grading for evaluation of EH on MRI, and iii) a proposed classification of EH based on its pathological significance. MRI evaluation revealed that EH exists extensively not only in ears with typical Meniere’s disease (MD), but also in those with various other otological disorders. The etiological classification of EH helps to summarize ideas for determining the pathophysiology of otological disorders, while a therapeutic classification provides clues to their management. MRI evaluations of EH have led to breakthroughs in investigations of EH in otological disorders. Precise grading for evaluation and clarification of EH on MRI based on its pathological significance could provide keys to elucidating the pathophysiology of EH-related otological disorders. Nagoya University 2022-08 /pmc/articles/PMC9529623/ /pubmed/36237884 http://dx.doi.org/10.18999/nagjms.84.3.497 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ).
spellingShingle Review Article
Sone, Michihiko
Yoshida, Tadao
Sugimoto, Satofumi
Kobayashi, Masumi
Teranishi, Masaaki
Naganawa, Shinji
Pathological significance and classification of endolymphatic hydrops in otological disorders
title Pathological significance and classification of endolymphatic hydrops in otological disorders
title_full Pathological significance and classification of endolymphatic hydrops in otological disorders
title_fullStr Pathological significance and classification of endolymphatic hydrops in otological disorders
title_full_unstemmed Pathological significance and classification of endolymphatic hydrops in otological disorders
title_short Pathological significance and classification of endolymphatic hydrops in otological disorders
title_sort pathological significance and classification of endolymphatic hydrops in otological disorders
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529623/
https://www.ncbi.nlm.nih.gov/pubmed/36237884
http://dx.doi.org/10.18999/nagjms.84.3.497
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