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A Fatal Etiology of Splenic Infarction
Hemophagocytic lymphohistiocytosis (HLH) is a rare systemic inflammatory disorder that is rapidly progressive and carries a poor prognosis. We present a case of HLH caused by undiagnosed B cell lymphoma, presenting initially with splenic infarction. Both HLH and splenic infarction are secondary cond...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Greater Baltimore Medical Center
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529637/ https://www.ncbi.nlm.nih.gov/pubmed/36262481 http://dx.doi.org/10.55729/2000-9666.1097 |
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author | Masterman, David Gandhi, Sonal Singh, Amteshwar Singh, Tanmay Kaur, Ashampreet |
author_facet | Masterman, David Gandhi, Sonal Singh, Amteshwar Singh, Tanmay Kaur, Ashampreet |
author_sort | Masterman, David |
collection | PubMed |
description | Hemophagocytic lymphohistiocytosis (HLH) is a rare systemic inflammatory disorder that is rapidly progressive and carries a poor prognosis. We present a case of HLH caused by undiagnosed B cell lymphoma, presenting initially with splenic infarction. Both HLH and splenic infarction are secondary conditions with a wide range of underlying etiologies. When either condition is identified, a prompt search for the underlying trigger is needed to prevent devastating consequences. We demonstrate the difficulties and barriers that can delay the diagnosis of HLH, and emphasize the importance of early treatment in improving survival rates. |
format | Online Article Text |
id | pubmed-9529637 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Greater Baltimore Medical Center |
record_format | MEDLINE/PubMed |
spelling | pubmed-95296372022-10-18 A Fatal Etiology of Splenic Infarction Masterman, David Gandhi, Sonal Singh, Amteshwar Singh, Tanmay Kaur, Ashampreet J Community Hosp Intern Med Perspect Case Report Hemophagocytic lymphohistiocytosis (HLH) is a rare systemic inflammatory disorder that is rapidly progressive and carries a poor prognosis. We present a case of HLH caused by undiagnosed B cell lymphoma, presenting initially with splenic infarction. Both HLH and splenic infarction are secondary conditions with a wide range of underlying etiologies. When either condition is identified, a prompt search for the underlying trigger is needed to prevent devastating consequences. We demonstrate the difficulties and barriers that can delay the diagnosis of HLH, and emphasize the importance of early treatment in improving survival rates. Greater Baltimore Medical Center 2022-09-09 /pmc/articles/PMC9529637/ /pubmed/36262481 http://dx.doi.org/10.55729/2000-9666.1097 Text en © 2022 Greater Baltimore Medical Center https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ). |
spellingShingle | Case Report Masterman, David Gandhi, Sonal Singh, Amteshwar Singh, Tanmay Kaur, Ashampreet A Fatal Etiology of Splenic Infarction |
title | A Fatal Etiology of Splenic Infarction |
title_full | A Fatal Etiology of Splenic Infarction |
title_fullStr | A Fatal Etiology of Splenic Infarction |
title_full_unstemmed | A Fatal Etiology of Splenic Infarction |
title_short | A Fatal Etiology of Splenic Infarction |
title_sort | fatal etiology of splenic infarction |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529637/ https://www.ncbi.nlm.nih.gov/pubmed/36262481 http://dx.doi.org/10.55729/2000-9666.1097 |
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