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A Fatal Etiology of Splenic Infarction

Hemophagocytic lymphohistiocytosis (HLH) is a rare systemic inflammatory disorder that is rapidly progressive and carries a poor prognosis. We present a case of HLH caused by undiagnosed B cell lymphoma, presenting initially with splenic infarction. Both HLH and splenic infarction are secondary cond...

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Detalles Bibliográficos
Autores principales: Masterman, David, Gandhi, Sonal, Singh, Amteshwar, Singh, Tanmay, Kaur, Ashampreet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Greater Baltimore Medical Center 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529637/
https://www.ncbi.nlm.nih.gov/pubmed/36262481
http://dx.doi.org/10.55729/2000-9666.1097
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author Masterman, David
Gandhi, Sonal
Singh, Amteshwar
Singh, Tanmay
Kaur, Ashampreet
author_facet Masterman, David
Gandhi, Sonal
Singh, Amteshwar
Singh, Tanmay
Kaur, Ashampreet
author_sort Masterman, David
collection PubMed
description Hemophagocytic lymphohistiocytosis (HLH) is a rare systemic inflammatory disorder that is rapidly progressive and carries a poor prognosis. We present a case of HLH caused by undiagnosed B cell lymphoma, presenting initially with splenic infarction. Both HLH and splenic infarction are secondary conditions with a wide range of underlying etiologies. When either condition is identified, a prompt search for the underlying trigger is needed to prevent devastating consequences. We demonstrate the difficulties and barriers that can delay the diagnosis of HLH, and emphasize the importance of early treatment in improving survival rates.
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spelling pubmed-95296372022-10-18 A Fatal Etiology of Splenic Infarction Masterman, David Gandhi, Sonal Singh, Amteshwar Singh, Tanmay Kaur, Ashampreet J Community Hosp Intern Med Perspect Case Report Hemophagocytic lymphohistiocytosis (HLH) is a rare systemic inflammatory disorder that is rapidly progressive and carries a poor prognosis. We present a case of HLH caused by undiagnosed B cell lymphoma, presenting initially with splenic infarction. Both HLH and splenic infarction are secondary conditions with a wide range of underlying etiologies. When either condition is identified, a prompt search for the underlying trigger is needed to prevent devastating consequences. We demonstrate the difficulties and barriers that can delay the diagnosis of HLH, and emphasize the importance of early treatment in improving survival rates. Greater Baltimore Medical Center 2022-09-09 /pmc/articles/PMC9529637/ /pubmed/36262481 http://dx.doi.org/10.55729/2000-9666.1097 Text en © 2022 Greater Baltimore Medical Center https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ).
spellingShingle Case Report
Masterman, David
Gandhi, Sonal
Singh, Amteshwar
Singh, Tanmay
Kaur, Ashampreet
A Fatal Etiology of Splenic Infarction
title A Fatal Etiology of Splenic Infarction
title_full A Fatal Etiology of Splenic Infarction
title_fullStr A Fatal Etiology of Splenic Infarction
title_full_unstemmed A Fatal Etiology of Splenic Infarction
title_short A Fatal Etiology of Splenic Infarction
title_sort fatal etiology of splenic infarction
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529637/
https://www.ncbi.nlm.nih.gov/pubmed/36262481
http://dx.doi.org/10.55729/2000-9666.1097
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