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Primary Mediastinal B-cell Lymphoma Presenting as Chest Pain in a Young Woman and Treated with EPOCH-R
Primary mediastinal B-cell lymphoma (PMBCL) is a rare type of diffuse large B-cell lymphoma, constituting 2–4% of non-Hodgkin lymphomas. Here we present a case of PMBCL initially presenting as pleuritic chest pain in an otherwise healthy 33-year-old woman. PMBCL typically presents as a large, fast-g...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Greater Baltimore Medical Center
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529639/ https://www.ncbi.nlm.nih.gov/pubmed/36262484 http://dx.doi.org/10.55729/2000-9666.1105 |
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author | Weidenbaum, Chloe Kushwah, Akanksha Geromes, Ariana Abbas, Jonathan A. |
author_facet | Weidenbaum, Chloe Kushwah, Akanksha Geromes, Ariana Abbas, Jonathan A. |
author_sort | Weidenbaum, Chloe |
collection | PubMed |
description | Primary mediastinal B-cell lymphoma (PMBCL) is a rare type of diffuse large B-cell lymphoma, constituting 2–4% of non-Hodgkin lymphomas. Here we present a case of PMBCL initially presenting as pleuritic chest pain in an otherwise healthy 33-year-old woman. PMBCL typically presents as a large, fast-growing tumor limited to the mediastinum, making the iliosacral involvement in this case unusual. R–CHOP is the most commonly used chemotherapy regimen, although more aggressive therapies like EPOCH-R can spare the need for consolidative radiation therapy. PMBCL represents one of the greatest diagnostic and therapeutic challenges in malignant hematology. |
format | Online Article Text |
id | pubmed-9529639 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Greater Baltimore Medical Center |
record_format | MEDLINE/PubMed |
spelling | pubmed-95296392022-10-18 Primary Mediastinal B-cell Lymphoma Presenting as Chest Pain in a Young Woman and Treated with EPOCH-R Weidenbaum, Chloe Kushwah, Akanksha Geromes, Ariana Abbas, Jonathan A. J Community Hosp Intern Med Perspect Case Report Primary mediastinal B-cell lymphoma (PMBCL) is a rare type of diffuse large B-cell lymphoma, constituting 2–4% of non-Hodgkin lymphomas. Here we present a case of PMBCL initially presenting as pleuritic chest pain in an otherwise healthy 33-year-old woman. PMBCL typically presents as a large, fast-growing tumor limited to the mediastinum, making the iliosacral involvement in this case unusual. R–CHOP is the most commonly used chemotherapy regimen, although more aggressive therapies like EPOCH-R can spare the need for consolidative radiation therapy. PMBCL represents one of the greatest diagnostic and therapeutic challenges in malignant hematology. Greater Baltimore Medical Center 2022-09-09 /pmc/articles/PMC9529639/ /pubmed/36262484 http://dx.doi.org/10.55729/2000-9666.1105 Text en © 2022 Greater Baltimore Medical Center https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ). |
spellingShingle | Case Report Weidenbaum, Chloe Kushwah, Akanksha Geromes, Ariana Abbas, Jonathan A. Primary Mediastinal B-cell Lymphoma Presenting as Chest Pain in a Young Woman and Treated with EPOCH-R |
title | Primary Mediastinal B-cell Lymphoma Presenting as Chest Pain in a Young Woman and Treated with EPOCH-R |
title_full | Primary Mediastinal B-cell Lymphoma Presenting as Chest Pain in a Young Woman and Treated with EPOCH-R |
title_fullStr | Primary Mediastinal B-cell Lymphoma Presenting as Chest Pain in a Young Woman and Treated with EPOCH-R |
title_full_unstemmed | Primary Mediastinal B-cell Lymphoma Presenting as Chest Pain in a Young Woman and Treated with EPOCH-R |
title_short | Primary Mediastinal B-cell Lymphoma Presenting as Chest Pain in a Young Woman and Treated with EPOCH-R |
title_sort | primary mediastinal b-cell lymphoma presenting as chest pain in a young woman and treated with epoch-r |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529639/ https://www.ncbi.nlm.nih.gov/pubmed/36262484 http://dx.doi.org/10.55729/2000-9666.1105 |
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