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Outcomes of Corneal Topographical Kmax readings 3 months after Corneal Cross Linkage in Keratoconus patients

BACKGROUND AND OBJECTIVE: Collagen protein, which is abundant in the cornea and has a triple helix form, may be found in almost every tissue matrix in the body. Natural cross connections between monomers provide the robustness of the helical protein structure. Wollensak and his colleagues developed...

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Autores principales: Sangah, Abdul Basit, Kumari, Jaya, Mumtaz, Hassan, Hasan, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Greater Baltimore Medical Center 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529647/
https://www.ncbi.nlm.nih.gov/pubmed/36262504
http://dx.doi.org/10.55729/2000-9666.1111
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author Sangah, Abdul Basit
Kumari, Jaya
Mumtaz, Hassan
Hasan, Mohammad
author_facet Sangah, Abdul Basit
Kumari, Jaya
Mumtaz, Hassan
Hasan, Mohammad
author_sort Sangah, Abdul Basit
collection PubMed
description BACKGROUND AND OBJECTIVE: Collagen protein, which is abundant in the cornea and has a triple helix form, may be found in almost every tissue matrix in the body. Natural cross connections between monomers provide the robustness of the helical protein structure. Wollensak and his colleagues developed the Dresden Protocol, a keratoconus treatment based on Corneal Cross-Linkage. We aimed to analyse and present the findings in individuals with progressive keratoconus using topographic and refractive results after corneal collagen crosslinking treatment (CXL) (KC) after 3 months. METHODS: The study comprises a total of 100 patients who were diagnosed with progressive KC and who underwent CXL between 2021 and 2022 at KRL Hospital Islamabad, Pakistan. All eyes in this study had a preoperative topography within 1 month before CXL treatment and the follow-ups were conducted at 3 months interval. RESULTS: In our investigation, 100 patients were added. The average age was 24.74 years. 77% of the patients were between the ages of 12 and 25 years, while 23% were between the ages of 26 and 50 years. In our survey, males made up 84% of the population, while females made up only 16%. The right eye was afflicted in 60% of cases, whereas the left eye was impacted in 40% of the population. Grade 2 Keratoconus affected 42% of patients, whereas Grade 1 Keratoconus affected 18%. Our findings were skewed toward men and the 12–25 age group, however in our recent study, we discovered considerable KC stability 3 months after CXL. CONCLUSION: Keratometric readings and visual acuity were stabilised or improved with CXL treatment. Keratoconus stability can be reached 3 months following the treatment, according to our findings.
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spelling pubmed-95296472022-10-18 Outcomes of Corneal Topographical Kmax readings 3 months after Corneal Cross Linkage in Keratoconus patients Sangah, Abdul Basit Kumari, Jaya Mumtaz, Hassan Hasan, Mohammad J Community Hosp Intern Med Perspect Research Article BACKGROUND AND OBJECTIVE: Collagen protein, which is abundant in the cornea and has a triple helix form, may be found in almost every tissue matrix in the body. Natural cross connections between monomers provide the robustness of the helical protein structure. Wollensak and his colleagues developed the Dresden Protocol, a keratoconus treatment based on Corneal Cross-Linkage. We aimed to analyse and present the findings in individuals with progressive keratoconus using topographic and refractive results after corneal collagen crosslinking treatment (CXL) (KC) after 3 months. METHODS: The study comprises a total of 100 patients who were diagnosed with progressive KC and who underwent CXL between 2021 and 2022 at KRL Hospital Islamabad, Pakistan. All eyes in this study had a preoperative topography within 1 month before CXL treatment and the follow-ups were conducted at 3 months interval. RESULTS: In our investigation, 100 patients were added. The average age was 24.74 years. 77% of the patients were between the ages of 12 and 25 years, while 23% were between the ages of 26 and 50 years. In our survey, males made up 84% of the population, while females made up only 16%. The right eye was afflicted in 60% of cases, whereas the left eye was impacted in 40% of the population. Grade 2 Keratoconus affected 42% of patients, whereas Grade 1 Keratoconus affected 18%. Our findings were skewed toward men and the 12–25 age group, however in our recent study, we discovered considerable KC stability 3 months after CXL. CONCLUSION: Keratometric readings and visual acuity were stabilised or improved with CXL treatment. Keratoconus stability can be reached 3 months following the treatment, according to our findings. Greater Baltimore Medical Center 2022-09-09 /pmc/articles/PMC9529647/ /pubmed/36262504 http://dx.doi.org/10.55729/2000-9666.1111 Text en © 2022 Greater Baltimore Medical Center https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ).
spellingShingle Research Article
Sangah, Abdul Basit
Kumari, Jaya
Mumtaz, Hassan
Hasan, Mohammad
Outcomes of Corneal Topographical Kmax readings 3 months after Corneal Cross Linkage in Keratoconus patients
title Outcomes of Corneal Topographical Kmax readings 3 months after Corneal Cross Linkage in Keratoconus patients
title_full Outcomes of Corneal Topographical Kmax readings 3 months after Corneal Cross Linkage in Keratoconus patients
title_fullStr Outcomes of Corneal Topographical Kmax readings 3 months after Corneal Cross Linkage in Keratoconus patients
title_full_unstemmed Outcomes of Corneal Topographical Kmax readings 3 months after Corneal Cross Linkage in Keratoconus patients
title_short Outcomes of Corneal Topographical Kmax readings 3 months after Corneal Cross Linkage in Keratoconus patients
title_sort outcomes of corneal topographical kmax readings 3 months after corneal cross linkage in keratoconus patients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529647/
https://www.ncbi.nlm.nih.gov/pubmed/36262504
http://dx.doi.org/10.55729/2000-9666.1111
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