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Structural insights of the elongation factor EF-Tu complexes in protein translation of Mycobacterium tuberculosis

Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is the second-deadliest infectious disease worldwide. Emerging evidence shows that the elongation factor EF-Tu could be an excellent target for treating Mtb infection. Here, we report the crystal structures of Mtb EF-Tu•EF-Ts and EF-Tu•GDP...

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Detalles Bibliográficos
Autores principales: Zhan, Bowen, Gao, Yanqing, Gao, Wenqing, Li, Ye, Li, Zhengyang, Qi, Qi, Lan, Xin, Shen, Hongbo, Gan, Jianhua, Zhao, Guoping, Li, Jixi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529903/
https://www.ncbi.nlm.nih.gov/pubmed/36192483
http://dx.doi.org/10.1038/s42003-022-04019-y