High-progesterone environment preserves T cell competency by evading glucocorticoid effects on immune regulation

Progesterone (P4) and glucocorticoid (GC) play crucial roles in the immunoregulation of a mother to accept and maintain a semi-allogenic fetus. P4 concentration increases during pregnancy and becomes much higher in the placenta than in the other peripheral tissues, wherein the concentration of corti...

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Detalles Bibliográficos
Autores principales: Kashiwagi, Hirofumi, Seki, Toshiro, Oshima, Shino, Ohno, Yusuke, Shimizu, Tomoka, Yamada, Soga, Katano, Nagi, Goto, Yumiko, Yasuda, Atsushi, Tsuda, Banri, Ito, Ryoji, Izumi, Shun-ichiro, Ishimoto, Hitoshi, Shiina, Takashi, Kametani, Yoshie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530059/
https://www.ncbi.nlm.nih.gov/pubmed/36203559
http://dx.doi.org/10.3389/fimmu.2022.1000728

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