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Remote diffusion-weighted imaging lesions and blood pressure variability in primary intracerebral hemorrhage
OBJECTIVE: The aim of this study was to examine the association between remote diffusion-weighted imaging lesions (R-DWILs) and blood pressure variability (BPV) in patients with primary intracerebral hemorrhage (ICH). METHODS: We conducted a retrospective review of a consecutive cohort of 375 patien...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530136/ https://www.ncbi.nlm.nih.gov/pubmed/36203972 http://dx.doi.org/10.3389/fneur.2022.950056 |
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author | Xu, Xuhua Peng, Shuangshuang Zhou, Yanli Li, Jiawen Tong, Lusha Gao, Feng |
author_facet | Xu, Xuhua Peng, Shuangshuang Zhou, Yanli Li, Jiawen Tong, Lusha Gao, Feng |
author_sort | Xu, Xuhua |
collection | PubMed |
description | OBJECTIVE: The aim of this study was to examine the association between remote diffusion-weighted imaging lesions (R-DWILs) and blood pressure variability (BPV) in patients with primary intracerebral hemorrhage (ICH). METHODS: We conducted a retrospective review of a consecutive cohort of 375 patients with primary ICH within 24 h onset. R-DWILs were defined as hyperintensity lesions in DWI remote from the hematoma. Blood pressure recordings were extracted up to 24 h post-admission. BPV was measured using SD, coefficient of variation (CV), and successive variation (SV). RESULTS: Remote DWI lesions were detected in 65 (17.3%) primary ICH patients. In multivariable logistic regression analysis, parameters of BPV were independently associated with R-DWILs, and the results remained consistent after being adjusted with mean SBP. SD, CV, and SV values in the highest quintile, showed 3- to 8-fold increased risk of R-DWILs, compared with the lowest quintile. ΔSBP demonstrated a significant difference in 2 different predictive models. Max SBP only dictated a significant difference in model 1. Mean SBP, admission SBP, and min SBP, failed to present an association with R-DWILs in model 1 or model 2. CONCLUSION: Our results provided additional evidence that BPV is associated with the development of R-DWILs in primary ICH. |
format | Online Article Text |
id | pubmed-9530136 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95301362022-10-05 Remote diffusion-weighted imaging lesions and blood pressure variability in primary intracerebral hemorrhage Xu, Xuhua Peng, Shuangshuang Zhou, Yanli Li, Jiawen Tong, Lusha Gao, Feng Front Neurol Neurology OBJECTIVE: The aim of this study was to examine the association between remote diffusion-weighted imaging lesions (R-DWILs) and blood pressure variability (BPV) in patients with primary intracerebral hemorrhage (ICH). METHODS: We conducted a retrospective review of a consecutive cohort of 375 patients with primary ICH within 24 h onset. R-DWILs were defined as hyperintensity lesions in DWI remote from the hematoma. Blood pressure recordings were extracted up to 24 h post-admission. BPV was measured using SD, coefficient of variation (CV), and successive variation (SV). RESULTS: Remote DWI lesions were detected in 65 (17.3%) primary ICH patients. In multivariable logistic regression analysis, parameters of BPV were independently associated with R-DWILs, and the results remained consistent after being adjusted with mean SBP. SD, CV, and SV values in the highest quintile, showed 3- to 8-fold increased risk of R-DWILs, compared with the lowest quintile. ΔSBP demonstrated a significant difference in 2 different predictive models. Max SBP only dictated a significant difference in model 1. Mean SBP, admission SBP, and min SBP, failed to present an association with R-DWILs in model 1 or model 2. CONCLUSION: Our results provided additional evidence that BPV is associated with the development of R-DWILs in primary ICH. Frontiers Media S.A. 2022-09-20 /pmc/articles/PMC9530136/ /pubmed/36203972 http://dx.doi.org/10.3389/fneur.2022.950056 Text en Copyright © 2022 Xu, Peng, Zhou, Li, Tong and Gao. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neurology Xu, Xuhua Peng, Shuangshuang Zhou, Yanli Li, Jiawen Tong, Lusha Gao, Feng Remote diffusion-weighted imaging lesions and blood pressure variability in primary intracerebral hemorrhage |
title | Remote diffusion-weighted imaging lesions and blood pressure variability in primary intracerebral hemorrhage |
title_full | Remote diffusion-weighted imaging lesions and blood pressure variability in primary intracerebral hemorrhage |
title_fullStr | Remote diffusion-weighted imaging lesions and blood pressure variability in primary intracerebral hemorrhage |
title_full_unstemmed | Remote diffusion-weighted imaging lesions and blood pressure variability in primary intracerebral hemorrhage |
title_short | Remote diffusion-weighted imaging lesions and blood pressure variability in primary intracerebral hemorrhage |
title_sort | remote diffusion-weighted imaging lesions and blood pressure variability in primary intracerebral hemorrhage |
topic | Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530136/ https://www.ncbi.nlm.nih.gov/pubmed/36203972 http://dx.doi.org/10.3389/fneur.2022.950056 |
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