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The utility of the 24-h delayed film of barium enema for detecting the dysganglionic bowel segment in Hirschsprung’s disease
BACKGROUND: Preoperative evaluation of the dysganglionic bowel segment is critical for establishing the optimal resection strategy for Hirschsprung’s disease (HSCR), which facilitates patient outcomes. OBJECTIVE: We set out to determine the utility of the 24-h delayed film of barium retention in pre...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530183/ https://www.ncbi.nlm.nih.gov/pubmed/36204664 http://dx.doi.org/10.3389/fped.2022.979149 |
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author | Zhou, Bingyan Wang, Di Chen, Ke Niu, Yonghua Jiao, Chunlei Zhu, Tianqi Feng, Jiexiong |
author_facet | Zhou, Bingyan Wang, Di Chen, Ke Niu, Yonghua Jiao, Chunlei Zhu, Tianqi Feng, Jiexiong |
author_sort | Zhou, Bingyan |
collection | PubMed |
description | BACKGROUND: Preoperative evaluation of the dysganglionic bowel segment is critical for establishing the optimal resection strategy for Hirschsprung’s disease (HSCR), which facilitates patient outcomes. OBJECTIVE: We set out to determine the utility of the 24-h delayed film of barium retention in predicting the length of dysganglionic bowel segment in HSCR. MATERIALS AND METHODS: A retrospective study of patients with clinically suspicious HSCR who underwent a preoperative 24-h delayed film of barium enema and were surgically treated from January 2015 to December 2019 was conducted. RESULTS: Two hundred and 58 patients were enrolled in this study. The sensitivity, specificity, positive and negative predictive values (NPVs) of the 24-h delayed film of barium enema to predict the neuropathological segment were 89.1, 91.5, 91.3, and 89.4%, respectively. The Youden index was 80.6%, with a kappa value of 0.806 (P < 0.001). The correlation rate between barium retention level and pathological results was 72.7% (16/22) when aganglionosis was restricted within the mid-distal rectum (short-segment type), increasing to 92.0% (46/50) and 93.5% (174/186) for patients that had aganglionosis extended beyond the mid-distal rectum (classical type) and sigmoid colon (long-segment type), respectively. Lastly, patients younger than 3 months showed a lower correlation rate (72.2%) compared to patients aged 3–12 months (91.0%) and > 12 months (92.6%). CONCLUSIONS: Our investigation of the 24-h delayed film of barium enema performed for patients suspected of having HSCR indicated that the barium retention level remains crucial in predicting dysganglionic bowel segment, which contributes to the decision-making for surgical physicians. |
format | Online Article Text |
id | pubmed-9530183 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95301832022-10-05 The utility of the 24-h delayed film of barium enema for detecting the dysganglionic bowel segment in Hirschsprung’s disease Zhou, Bingyan Wang, Di Chen, Ke Niu, Yonghua Jiao, Chunlei Zhu, Tianqi Feng, Jiexiong Front Pediatr Pediatrics BACKGROUND: Preoperative evaluation of the dysganglionic bowel segment is critical for establishing the optimal resection strategy for Hirschsprung’s disease (HSCR), which facilitates patient outcomes. OBJECTIVE: We set out to determine the utility of the 24-h delayed film of barium retention in predicting the length of dysganglionic bowel segment in HSCR. MATERIALS AND METHODS: A retrospective study of patients with clinically suspicious HSCR who underwent a preoperative 24-h delayed film of barium enema and were surgically treated from January 2015 to December 2019 was conducted. RESULTS: Two hundred and 58 patients were enrolled in this study. The sensitivity, specificity, positive and negative predictive values (NPVs) of the 24-h delayed film of barium enema to predict the neuropathological segment were 89.1, 91.5, 91.3, and 89.4%, respectively. The Youden index was 80.6%, with a kappa value of 0.806 (P < 0.001). The correlation rate between barium retention level and pathological results was 72.7% (16/22) when aganglionosis was restricted within the mid-distal rectum (short-segment type), increasing to 92.0% (46/50) and 93.5% (174/186) for patients that had aganglionosis extended beyond the mid-distal rectum (classical type) and sigmoid colon (long-segment type), respectively. Lastly, patients younger than 3 months showed a lower correlation rate (72.2%) compared to patients aged 3–12 months (91.0%) and > 12 months (92.6%). CONCLUSIONS: Our investigation of the 24-h delayed film of barium enema performed for patients suspected of having HSCR indicated that the barium retention level remains crucial in predicting dysganglionic bowel segment, which contributes to the decision-making for surgical physicians. Frontiers Media S.A. 2022-09-20 /pmc/articles/PMC9530183/ /pubmed/36204664 http://dx.doi.org/10.3389/fped.2022.979149 Text en Copyright © 2022 Zhou, Wang, Chen, Niu, Jiao, Zhu and Feng. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pediatrics Zhou, Bingyan Wang, Di Chen, Ke Niu, Yonghua Jiao, Chunlei Zhu, Tianqi Feng, Jiexiong The utility of the 24-h delayed film of barium enema for detecting the dysganglionic bowel segment in Hirschsprung’s disease |
title | The utility of the 24-h delayed film of barium enema for detecting the dysganglionic bowel segment in Hirschsprung’s disease |
title_full | The utility of the 24-h delayed film of barium enema for detecting the dysganglionic bowel segment in Hirschsprung’s disease |
title_fullStr | The utility of the 24-h delayed film of barium enema for detecting the dysganglionic bowel segment in Hirschsprung’s disease |
title_full_unstemmed | The utility of the 24-h delayed film of barium enema for detecting the dysganglionic bowel segment in Hirschsprung’s disease |
title_short | The utility of the 24-h delayed film of barium enema for detecting the dysganglionic bowel segment in Hirschsprung’s disease |
title_sort | utility of the 24-h delayed film of barium enema for detecting the dysganglionic bowel segment in hirschsprung’s disease |
topic | Pediatrics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530183/ https://www.ncbi.nlm.nih.gov/pubmed/36204664 http://dx.doi.org/10.3389/fped.2022.979149 |
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