Cargando…

The utility of the 24-h delayed film of barium enema for detecting the dysganglionic bowel segment in Hirschsprung’s disease

BACKGROUND: Preoperative evaluation of the dysganglionic bowel segment is critical for establishing the optimal resection strategy for Hirschsprung’s disease (HSCR), which facilitates patient outcomes. OBJECTIVE: We set out to determine the utility of the 24-h delayed film of barium retention in pre...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Bingyan, Wang, Di, Chen, Ke, Niu, Yonghua, Jiao, Chunlei, Zhu, Tianqi, Feng, Jiexiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530183/
https://www.ncbi.nlm.nih.gov/pubmed/36204664
http://dx.doi.org/10.3389/fped.2022.979149
_version_ 1784801622524690432
author Zhou, Bingyan
Wang, Di
Chen, Ke
Niu, Yonghua
Jiao, Chunlei
Zhu, Tianqi
Feng, Jiexiong
author_facet Zhou, Bingyan
Wang, Di
Chen, Ke
Niu, Yonghua
Jiao, Chunlei
Zhu, Tianqi
Feng, Jiexiong
author_sort Zhou, Bingyan
collection PubMed
description BACKGROUND: Preoperative evaluation of the dysganglionic bowel segment is critical for establishing the optimal resection strategy for Hirschsprung’s disease (HSCR), which facilitates patient outcomes. OBJECTIVE: We set out to determine the utility of the 24-h delayed film of barium retention in predicting the length of dysganglionic bowel segment in HSCR. MATERIALS AND METHODS: A retrospective study of patients with clinically suspicious HSCR who underwent a preoperative 24-h delayed film of barium enema and were surgically treated from January 2015 to December 2019 was conducted. RESULTS: Two hundred and 58 patients were enrolled in this study. The sensitivity, specificity, positive and negative predictive values (NPVs) of the 24-h delayed film of barium enema to predict the neuropathological segment were 89.1, 91.5, 91.3, and 89.4%, respectively. The Youden index was 80.6%, with a kappa value of 0.806 (P < 0.001). The correlation rate between barium retention level and pathological results was 72.7% (16/22) when aganglionosis was restricted within the mid-distal rectum (short-segment type), increasing to 92.0% (46/50) and 93.5% (174/186) for patients that had aganglionosis extended beyond the mid-distal rectum (classical type) and sigmoid colon (long-segment type), respectively. Lastly, patients younger than 3 months showed a lower correlation rate (72.2%) compared to patients aged 3–12 months (91.0%) and > 12 months (92.6%). CONCLUSIONS: Our investigation of the 24-h delayed film of barium enema performed for patients suspected of having HSCR indicated that the barium retention level remains crucial in predicting dysganglionic bowel segment, which contributes to the decision-making for surgical physicians.
format Online
Article
Text
id pubmed-9530183
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-95301832022-10-05 The utility of the 24-h delayed film of barium enema for detecting the dysganglionic bowel segment in Hirschsprung’s disease Zhou, Bingyan Wang, Di Chen, Ke Niu, Yonghua Jiao, Chunlei Zhu, Tianqi Feng, Jiexiong Front Pediatr Pediatrics BACKGROUND: Preoperative evaluation of the dysganglionic bowel segment is critical for establishing the optimal resection strategy for Hirschsprung’s disease (HSCR), which facilitates patient outcomes. OBJECTIVE: We set out to determine the utility of the 24-h delayed film of barium retention in predicting the length of dysganglionic bowel segment in HSCR. MATERIALS AND METHODS: A retrospective study of patients with clinically suspicious HSCR who underwent a preoperative 24-h delayed film of barium enema and were surgically treated from January 2015 to December 2019 was conducted. RESULTS: Two hundred and 58 patients were enrolled in this study. The sensitivity, specificity, positive and negative predictive values (NPVs) of the 24-h delayed film of barium enema to predict the neuropathological segment were 89.1, 91.5, 91.3, and 89.4%, respectively. The Youden index was 80.6%, with a kappa value of 0.806 (P < 0.001). The correlation rate between barium retention level and pathological results was 72.7% (16/22) when aganglionosis was restricted within the mid-distal rectum (short-segment type), increasing to 92.0% (46/50) and 93.5% (174/186) for patients that had aganglionosis extended beyond the mid-distal rectum (classical type) and sigmoid colon (long-segment type), respectively. Lastly, patients younger than 3 months showed a lower correlation rate (72.2%) compared to patients aged 3–12 months (91.0%) and > 12 months (92.6%). CONCLUSIONS: Our investigation of the 24-h delayed film of barium enema performed for patients suspected of having HSCR indicated that the barium retention level remains crucial in predicting dysganglionic bowel segment, which contributes to the decision-making for surgical physicians. Frontiers Media S.A. 2022-09-20 /pmc/articles/PMC9530183/ /pubmed/36204664 http://dx.doi.org/10.3389/fped.2022.979149 Text en Copyright © 2022 Zhou, Wang, Chen, Niu, Jiao, Zhu and Feng. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Zhou, Bingyan
Wang, Di
Chen, Ke
Niu, Yonghua
Jiao, Chunlei
Zhu, Tianqi
Feng, Jiexiong
The utility of the 24-h delayed film of barium enema for detecting the dysganglionic bowel segment in Hirschsprung’s disease
title The utility of the 24-h delayed film of barium enema for detecting the dysganglionic bowel segment in Hirschsprung’s disease
title_full The utility of the 24-h delayed film of barium enema for detecting the dysganglionic bowel segment in Hirschsprung’s disease
title_fullStr The utility of the 24-h delayed film of barium enema for detecting the dysganglionic bowel segment in Hirschsprung’s disease
title_full_unstemmed The utility of the 24-h delayed film of barium enema for detecting the dysganglionic bowel segment in Hirschsprung’s disease
title_short The utility of the 24-h delayed film of barium enema for detecting the dysganglionic bowel segment in Hirschsprung’s disease
title_sort utility of the 24-h delayed film of barium enema for detecting the dysganglionic bowel segment in hirschsprung’s disease
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530183/
https://www.ncbi.nlm.nih.gov/pubmed/36204664
http://dx.doi.org/10.3389/fped.2022.979149
work_keys_str_mv AT zhoubingyan theutilityofthe24hdelayedfilmofbariumenemafordetectingthedysganglionicbowelsegmentinhirschsprungsdisease
AT wangdi theutilityofthe24hdelayedfilmofbariumenemafordetectingthedysganglionicbowelsegmentinhirschsprungsdisease
AT chenke theutilityofthe24hdelayedfilmofbariumenemafordetectingthedysganglionicbowelsegmentinhirschsprungsdisease
AT niuyonghua theutilityofthe24hdelayedfilmofbariumenemafordetectingthedysganglionicbowelsegmentinhirschsprungsdisease
AT jiaochunlei theutilityofthe24hdelayedfilmofbariumenemafordetectingthedysganglionicbowelsegmentinhirschsprungsdisease
AT zhutianqi theutilityofthe24hdelayedfilmofbariumenemafordetectingthedysganglionicbowelsegmentinhirschsprungsdisease
AT fengjiexiong theutilityofthe24hdelayedfilmofbariumenemafordetectingthedysganglionicbowelsegmentinhirschsprungsdisease
AT zhoubingyan utilityofthe24hdelayedfilmofbariumenemafordetectingthedysganglionicbowelsegmentinhirschsprungsdisease
AT wangdi utilityofthe24hdelayedfilmofbariumenemafordetectingthedysganglionicbowelsegmentinhirschsprungsdisease
AT chenke utilityofthe24hdelayedfilmofbariumenemafordetectingthedysganglionicbowelsegmentinhirschsprungsdisease
AT niuyonghua utilityofthe24hdelayedfilmofbariumenemafordetectingthedysganglionicbowelsegmentinhirschsprungsdisease
AT jiaochunlei utilityofthe24hdelayedfilmofbariumenemafordetectingthedysganglionicbowelsegmentinhirschsprungsdisease
AT zhutianqi utilityofthe24hdelayedfilmofbariumenemafordetectingthedysganglionicbowelsegmentinhirschsprungsdisease
AT fengjiexiong utilityofthe24hdelayedfilmofbariumenemafordetectingthedysganglionicbowelsegmentinhirschsprungsdisease