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Regulation of the cecal microbiota community and the fatty liver deposition by the addition of brewers’ spent grain to feed of Landes geese

The effects of brewers’ spent grain (BSG) diets on the fatty liver deposition and the cecal microbial community were investigated in a total of 320 healthy 5-day-old Landes geese. These geese were randomly and evenly divided into 4 groups each containing 8 replicates and 10 geese per replicate. Thes...

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Autores principales: Xu, Ping, Hong, Yuxuan, Chen, Pinpin, Wang, Xu, Li, Shijie, Wang, Jie, Meng, Fancong, Zhou, Zutao, Shi, Deshi, Li, Zili, Cao, Shengbo, Xiao, Yuncai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530188/
https://www.ncbi.nlm.nih.gov/pubmed/36204629
http://dx.doi.org/10.3389/fmicb.2022.970563
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author Xu, Ping
Hong, Yuxuan
Chen, Pinpin
Wang, Xu
Li, Shijie
Wang, Jie
Meng, Fancong
Zhou, Zutao
Shi, Deshi
Li, Zili
Cao, Shengbo
Xiao, Yuncai
author_facet Xu, Ping
Hong, Yuxuan
Chen, Pinpin
Wang, Xu
Li, Shijie
Wang, Jie
Meng, Fancong
Zhou, Zutao
Shi, Deshi
Li, Zili
Cao, Shengbo
Xiao, Yuncai
author_sort Xu, Ping
collection PubMed
description The effects of brewers’ spent grain (BSG) diets on the fatty liver deposition and the cecal microbial community were investigated in a total of 320 healthy 5-day-old Landes geese. These geese were randomly and evenly divided into 4 groups each containing 8 replicates and 10 geese per replicate. These four groups of geese were fed from the rearing stage (days 5–60) to the overfeeding stage (days 61–90). The Landes geese in group C (control) were fed with basal diet (days 5–90); group B fed first with basal diet in the rearing stage and then basal diet + 4% BSG in the overfeeding stage; group F first with basal diet + 4% BSG during the rearing stage and then basal diet in the overfeeding stage; and group W with basal diet + 4% BSG (days 5–90). The results showed that during the rearing stage, the body weight (BW) and the average daily gain (ADG) of Landes geese were significantly increased in groups F and W, while during the overfeeding stage, the liver weights of groups W and B were significantly higher than that of group C. The taxonomic structure of the intestinal microbiota revealed that during the overfeeding period, the relative abundance of Bacteroides in group W was increased compared to group C, while the relative abundances of Escherichia–Shigella and prevotellaceae_Ga6A1_group were decreased. Results of the transcriptomics analysis showed that addition of BSG to Landes geese diets altered the expression of genes involved in PI3K-Akt signaling pathway and sphingolipid metabolism in the liver. Our study provided novel experimental evidence based on the cecal microbiota to support the application of BSG in the regulation of fatty liver deposition by modulating the gut microbiota in Landes geese.
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spelling pubmed-95301882022-10-05 Regulation of the cecal microbiota community and the fatty liver deposition by the addition of brewers’ spent grain to feed of Landes geese Xu, Ping Hong, Yuxuan Chen, Pinpin Wang, Xu Li, Shijie Wang, Jie Meng, Fancong Zhou, Zutao Shi, Deshi Li, Zili Cao, Shengbo Xiao, Yuncai Front Microbiol Microbiology The effects of brewers’ spent grain (BSG) diets on the fatty liver deposition and the cecal microbial community were investigated in a total of 320 healthy 5-day-old Landes geese. These geese were randomly and evenly divided into 4 groups each containing 8 replicates and 10 geese per replicate. These four groups of geese were fed from the rearing stage (days 5–60) to the overfeeding stage (days 61–90). The Landes geese in group C (control) were fed with basal diet (days 5–90); group B fed first with basal diet in the rearing stage and then basal diet + 4% BSG in the overfeeding stage; group F first with basal diet + 4% BSG during the rearing stage and then basal diet in the overfeeding stage; and group W with basal diet + 4% BSG (days 5–90). The results showed that during the rearing stage, the body weight (BW) and the average daily gain (ADG) of Landes geese were significantly increased in groups F and W, while during the overfeeding stage, the liver weights of groups W and B were significantly higher than that of group C. The taxonomic structure of the intestinal microbiota revealed that during the overfeeding period, the relative abundance of Bacteroides in group W was increased compared to group C, while the relative abundances of Escherichia–Shigella and prevotellaceae_Ga6A1_group were decreased. Results of the transcriptomics analysis showed that addition of BSG to Landes geese diets altered the expression of genes involved in PI3K-Akt signaling pathway and sphingolipid metabolism in the liver. Our study provided novel experimental evidence based on the cecal microbiota to support the application of BSG in the regulation of fatty liver deposition by modulating the gut microbiota in Landes geese. Frontiers Media S.A. 2022-09-20 /pmc/articles/PMC9530188/ /pubmed/36204629 http://dx.doi.org/10.3389/fmicb.2022.970563 Text en Copyright © 2022 Xu, Hong, Chen, Wang, Li, Wang, Meng, Zhou, Shi, Li, Cao and Xiao. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Xu, Ping
Hong, Yuxuan
Chen, Pinpin
Wang, Xu
Li, Shijie
Wang, Jie
Meng, Fancong
Zhou, Zutao
Shi, Deshi
Li, Zili
Cao, Shengbo
Xiao, Yuncai
Regulation of the cecal microbiota community and the fatty liver deposition by the addition of brewers’ spent grain to feed of Landes geese
title Regulation of the cecal microbiota community and the fatty liver deposition by the addition of brewers’ spent grain to feed of Landes geese
title_full Regulation of the cecal microbiota community and the fatty liver deposition by the addition of brewers’ spent grain to feed of Landes geese
title_fullStr Regulation of the cecal microbiota community and the fatty liver deposition by the addition of brewers’ spent grain to feed of Landes geese
title_full_unstemmed Regulation of the cecal microbiota community and the fatty liver deposition by the addition of brewers’ spent grain to feed of Landes geese
title_short Regulation of the cecal microbiota community and the fatty liver deposition by the addition of brewers’ spent grain to feed of Landes geese
title_sort regulation of the cecal microbiota community and the fatty liver deposition by the addition of brewers’ spent grain to feed of landes geese
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530188/
https://www.ncbi.nlm.nih.gov/pubmed/36204629
http://dx.doi.org/10.3389/fmicb.2022.970563
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