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Receptor-informed network control theory links LSD and psilocybin to a flattening of the brain’s control energy landscape

Psychedelics including lysergic acid diethylamide (LSD) and psilocybin temporarily alter subjective experience through their neurochemical effects. Serotonin 2a (5-HT2a) receptor agonism by these compounds is associated with more diverse (entropic) brain activity. We postulate that this increase in...

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Detalles Bibliográficos
Autores principales: Singleton, S. Parker, Luppi, Andrea I., Carhart-Harris, Robin L., Cruzat, Josephine, Roseman, Leor, Nutt, David J., Deco, Gustavo, Kringelbach, Morten L., Stamatakis, Emmanuel A., Kuceyeski, Amy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530221/
https://www.ncbi.nlm.nih.gov/pubmed/36192411
http://dx.doi.org/10.1038/s41467-022-33578-1