Cargando…

Receptor-informed network control theory links LSD and psilocybin to a flattening of the brain’s control energy landscape

Psychedelics including lysergic acid diethylamide (LSD) and psilocybin temporarily alter subjective experience through their neurochemical effects. Serotonin 2a (5-HT2a) receptor agonism by these compounds is associated with more diverse (entropic) brain activity. We postulate that this increase in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Singleton, S. Parker, Luppi, Andrea I., Carhart-Harris, Robin L., Cruzat, Josephine, Roseman, Leor, Nutt, David J., Deco, Gustavo, Kringelbach, Morten L., Stamatakis, Emmanuel A., Kuceyeski, Amy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530221/ https://www.ncbi.nlm.nih.gov/pubmed/36192411 http://dx.doi.org/10.1038/s41467-022-33578-1

Ejemplares similares

Connectome-harmonic decomposition of human brain activity reveals dynamical repertoire re-organization under LSD
por: Atasoy, Selen, et al.
Publicado: (2017)

Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression
por: Roseman, Leor, et al.
Publicado: (2018)

Increased sensitivity to strong perturbations in a whole-brain model of LSD
por: Jobst, Beatrice M., et al.
Publicado: (2021)

LSD alters dynamic integration and segregation in the human brain
por: Luppi, Andrea I., et al.
Publicado: (2021)

Time-resolved network control analysis links reduced control energy under DMT with the serotonin 2a receptor, signal diversity, and subjective experience
por: Singleton, S. Parker, et al.
Publicado: (2023)

The effects of psilocybin and MDMA on between-network resting state functional connectivity in healthy volunteers
por: Roseman, Leor, et al.
Publicado: (2014)

Changes in music-evoked emotion and ventral striatal functional connectivity after psilocybin therapy for depression
por: Shukuroglou, Melissa, et al.
Publicado: (2022)

Effects of psilocybin versus escitalopram on rumination and thought suppression in depression
por: Barba, Tommaso, et al.
Publicado: (2022)

Effects of psilocybin therapy on personality structure
por: Erritzoe, D., et al.
Publicado: (2018)

Brain songs framework used for discovering the relevant timescale of the human brain
por: Deco, Gustavo, et al.
Publicado: (2019)

Body mass index (BMI) does not predict responses to psilocybin
por: Spriggs, Meg J, et al.
Publicado: (2022)

Increased spontaneous MEG signal diversity for psychoactive doses of ketamine, LSD and psilocybin
por: Schartner, Michael M., et al.
Publicado: (2017)

LSD-induced increase of Ising temperature and algorithmic complexity of brain dynamics
por: Ruffini, Giulio, et al.
Publicado: (2023)

Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms
por: Carhart-Harris, Robin L, et al.
Publicado: (2017)

Toward naturalistic neuroscience: Mechanisms underlying the flattening of brain hierarchy in movie-watching compared to rest and task
por: Kringelbach, Morten L., et al.
Publicado: (2023)

Flashback phenomena after administration of LSD and psilocybin in controlled studies with healthy participants
por: Müller, Felix, et al.
Publicado: (2022)

Co-use of MDMA with psilocybin/LSD may buffer against challenging experiences and enhance positive experiences
por: Zeifman, Richard J., et al.
Publicado: (2023)

Dynamic coupling of whole-brain neuronal and neurotransmitter systems
por: Kringelbach, Morten L., et al.
Publicado: (2020)

Psilocybin and MDMA reduce costly punishment in the Ultimatum Game
por: Gabay, Anthony S., et al.
Publicado: (2018)

Awakening: Predicting external stimulation to force transitions between different brain states
por: Deco, Gustavo, et al.
Publicado: (2019)

Model-based whole-brain perturbational landscape of neurodegenerative diseases
por: Sanz Perl, Yonatan, et al.
Publicado: (2023)

Psilocybin with psychological support improves emotional face recognition in treatment-resistant depression
por: Stroud, J. B., et al.
Publicado: (2017)

A critical evaluation of QIDS-SR-16 using data from a trial of psilocybin therapy versus escitalopram treatment for depression
por: Weiss, Brandon, et al.
Publicado: (2023)

Development of the Psychological Insight Questionnaire among a sample of people who have consumed psilocybin or LSD
por: Davis, Alan K, et al.
Publicado: (2021)

Therapeutic Alliance and Rapport Modulate Responses to Psilocybin Assisted Therapy for Depression
por: Murphy, Roberta, et al.
Publicado: (2022)

Increased nature relatedness and decreased authoritarian political views after psilocybin for treatment-resistant depression
por: Lyons, Taylor, et al.
Publicado: (2018)

Temporal Irreversibility of Large-Scale Brain Dynamics in Alzheimer’s Disease
por: Cruzat, Josephine, et al.
Publicado: (2023)

Effect of lysergic acid diethylamide (LSD) on reinforcement learning in humans
por: Kanen, Jonathan W., et al.
Publicado: (2023)

Study Protocol for “Psilocybin as a Treatment for Anorexia Nervosa: A Pilot Study”
por: Spriggs, Meg J., et al.
Publicado: (2021)

More Realistic Forecasting of Future Life Events After Psilocybin for Treatment-Resistant Depression
por: Lyons, Taylor, et al.
Publicado: (2018)

Turbulent-like Dynamics in the Human Brain
por: Deco, Gustavo, et al.
Publicado: (2020)

Psilocybin with psychological support for treatment-resistant depression: six-month follow-up
por: Carhart-Harris, R. L., et al.
Publicado: (2017)

DMT Models the Near-Death Experience
por: Timmermann, Christopher, et al.
Publicado: (2018)

Psilocybin and Mental Health–Don't Lose Control
por: Barnby, Joseph M., et al.
Publicado: (2018)

Dynamical consequences of regional heterogeneity in the brain’s transcriptional landscape
por: Deco, Gustavo, et al.
Publicado: (2021)

The hidden therapist: evidence for a central role of music in psychedelic therapy
por: Kaelen, Mendel, et al.
Publicado: (2018)

Correction to: The hidden therapist: evidence for a central role of music in psychedelic therapy
por: Kaelen, Mendel, et al.
Publicado: (2018)

Distributed harmonic patterns of structure-function dependence orchestrate human consciousness
por: Luppi, Andrea I., et al.
Publicado: (2023)

Revisiting the global workspace orchestrating the hierarchical organization of the human brain
por: Deco, Gustavo, et al.
Publicado: (2021)

Among psychedelic-experienced users, only past use of psilocybin reliably predicts nature relatedness
por: Forstmann, Matthias, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_eanbmbg4e8poeg1cfcsbhpqrh1