DHRS2 inhibits cell growth and metastasis in ovarian cancer by downregulation of CHKα to disrupt choline metabolism

The short-chain dehydrogenase/reductase (SDR) superfamily has essential roles in lipid metabolism and redox sensing. In recent years, accumulating evidence highlights the emerging association between SDR family enzymes and cancer. Dehydrogenase/reductase member 2(DHRS2) belongs to the NADH/NADPH-dep...

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Detalles Bibliográficos
Autores principales: Li, Zhenzhen, Tan, Yue, Li, Xiang, Quan, Jing, Bode, Ann M., Cao, Ya, Luo, Xiangjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530226/
https://www.ncbi.nlm.nih.gov/pubmed/36192391
http://dx.doi.org/10.1038/s41419-022-05291-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530226/
https://www.ncbi.nlm.nih.gov/pubmed/36192391
http://dx.doi.org/10.1038/s41419-022-05291-w

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