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DHRS2 inhibits cell growth and metastasis in ovarian cancer by downregulation of CHKα to disrupt choline metabolism
The short-chain dehydrogenase/reductase (SDR) superfamily has essential roles in lipid metabolism and redox sensing. In recent years, accumulating evidence highlights the emerging association between SDR family enzymes and cancer. Dehydrogenase/reductase member 2(DHRS2) belongs to the NADH/NADPH-dep...
Autores principales: | Li, Zhenzhen, Tan, Yue, Li, Xiang, Quan, Jing, Bode, Ann M., Cao, Ya, Luo, Xiangjian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530226/ https://www.ncbi.nlm.nih.gov/pubmed/36192391 http://dx.doi.org/10.1038/s41419-022-05291-w |
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