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Macromolecular crowding and supersaturation protect hemodialysis patients from the onset of dialysis-related amyloidosis
Dialysis-related amyloidosis (DRA), a serious complication among long-term hemodialysis patients, is caused by amyloid fibrils of β2-microglobulin (β2m). Although high serum β2m levels and a long dialysis vintage are the primary and secondary risk factors for the onset of DRA, respectively, patients...
Autores principales: | Nakajima, Kichitaro, Yamaguchi, Keiichi, Noji, Masahiro, Aguirre, César, Ikenaka, Kensuke, Mochizuki, Hideki, Zhou, Lianjie, Ogi, Hirotsugu, Ito, Toru, Narita, Ichiei, Gejyo, Fumitake, Naiki, Hironobu, Yamamoto, Suguru, Goto, Yuji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530240/ https://www.ncbi.nlm.nih.gov/pubmed/36192385 http://dx.doi.org/10.1038/s41467-022-33247-3 |
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