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NRF2-directed PRPS1 upregulation to promote the progression and metastasis of melanoma

Phosphoribosyl pyrophosphate synthetase 1 (PRPS1) is the first enzyme in the de novo purine nucleotide synthesis pathway and is essential for cell development. However, the effect of PRPS1 on melanoma proliferation and metastasis remains unclear. This study aimed to investigate the regulatory mechan...

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Detalles Bibliográficos
Autores principales:	Xiong, Guohang, Feng, Yu, Yi, Xiaojia, Zhang, Xuedan, Li, Xiaoyu, Yang, Lijuan, Yi, Zihan, Sai, Buqing, Yang, Zhe, Zhang, Qiao, Kuang, Yingmin, Zhu, Yuechun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530353/ https://www.ncbi.nlm.nih.gov/pubmed/36203561 http://dx.doi.org/10.3389/fimmu.2022.989263

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