Degradation of ribosomal and chaperone proteins is attenuated during the differentiation of replicatively aged C2C12 myoblasts

BACKGROUND: Cell assays are important for investigating the mechanisms of ageing, including losses in protein homeostasis and ‘proteostasis collapse’. We used novel isotopic labelling and proteomic methods to investigate protein turnover in replicatively aged (>140 population doublings) murine C2...

Descripción completa

Detalles Bibliográficos
Autores principales: Brown, Alexander D., Stewart, Claire E., Burniston, Jatin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530526/
https://www.ncbi.nlm.nih.gov/pubmed/35819316
http://dx.doi.org/10.1002/jcsm.13034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530526/
https://www.ncbi.nlm.nih.gov/pubmed/35819316
http://dx.doi.org/10.1002/jcsm.13034

Ejemplares similares