Cargando…
A combination vaccine against SARS-CoV-2 and H1N1 influenza based on receptor binding domain trimerized by six-helix bundle fusion core
BACKGROUND: Increasing severe morbidity and mortality by simultaneous or sequential infections with SARS-CoV-2 and influenza A viruses (IAV), especially in the elderly and obese patients, highlight the urgency of developing a combination vaccine against COVID-19 and influenza. METHODS: Self-assembli...
Autores principales: | Shi, Rui, Zeng, Jiawei, Xu, Ling, Wang, Fengze, Duan, Xiaomin, Wang, Yue, Wu, Zheng, Yu, Dandan, Huang, Qingrui, Yao, Yong-Gang, Yan, Jinghua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530591/ https://www.ncbi.nlm.nih.gov/pubmed/36206623 http://dx.doi.org/10.1016/j.ebiom.2022.104297 |
Ejemplares similares
-
Evidence That the Transition of HIV-1 Gp41 into a Six-Helix Bundle, Not the Bundle Configuration, Induces Membrane Fusion
por: Melikyan, Grigory B., et al.
Publicado: (2000) -
Resistance to N-peptide fusion inhibitors correlates with thermodynamic stability of the gp41 six-helix bundle but not HIV entry kinetics
por: De Feo, Christopher J, et al.
Publicado: (2014) -
CryoET structures of immature HIV Gag reveal six-helix bundle
por: Mendonça, Luiza, et al.
Publicado: (2021) -
Salvianolic acid C potently inhibits SARS-CoV-2 infection by blocking the formation of six-helix bundle core of spike protein
por: Yang, Chan, et al.
Publicado: (2020) -
Early Steps of HIV-1 Fusion Define the Sensitivity to Inhibitory Peptides That Block 6-Helix Bundle Formation
por: Miyauchi, Kosuke, et al.
Publicado: (2009)