Characterization of light chain c-terminal extension sequence variant in one bispecific antibody

Protein modifications such as post-translational modifications (PTMs) and sequence variants (SVs) occur frequently during protein biosynthesis and have received great attention by biopharma industry and regulatory agencies. In this study, an aberrant peak near light chain (LC) was observed in the no...

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Detalles Bibliográficos
Autores principales: Lin, Jun, Xie, Mengyu, Liu, Dan, Gao, Zhen, Zhao, Xiaoyan, Ma, Hongxia, Ding, Sheng, Li, Shu mei, Li, Song, Liu, Yanling, Zhou, Fang, Hu, Hao, Chen, Tao, Chen, He, Xie, Min, Yang, Bo, Cheng, Jun, Ma, Mingjun, Nan, Yanyang, Ju, Dianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530627/
https://www.ncbi.nlm.nih.gov/pubmed/36204149
http://dx.doi.org/10.3389/fchem.2022.994472

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