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A computational study of the structure and function of human Zrt and Irt-like proteins metal transporters: An elevator-type transport mechanism predicted by AlphaFold2

The ZIP (Zrt and Irt-like proteins) protein family includes transporters responsible for the translocation of zinc and other transition metals, such as iron and cadmium, between the extracellular space (or the lumen of organelles) and the cytoplasm. This protein family is present at all the phylogen...

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Detalles Bibliográficos
Autores principales: Pasquadibisceglie, Andrea, Leccese, Adriana, Polticelli, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530640/
https://www.ncbi.nlm.nih.gov/pubmed/36204150
http://dx.doi.org/10.3389/fchem.2022.1004815