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Pan-Cancer Analysis Reveals Recurrent BCAR4 Gene Fusions across Solid Tumors

Chromosomal rearrangements often result in active regulatory regions juxtaposed upstream of an oncogene to generate an expressed gene fusion. Repeated activation of a common downstream partner–with differing upstream regions across a patient cohort–suggests a conserved oncogenic role. Analysis of 9,...

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Detalles Bibliográficos
Autores principales: Nickless, Andrew, Zhang, Jin, Othoum, Ghofran, Webster, Jace, Inkman, Matthew J., Coonrod, Emily, Fontes, Sherron, Rozycki, Emily B., Maher, Christopher A., White, Nicole M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530645/
https://www.ncbi.nlm.nih.gov/pubmed/35852383
http://dx.doi.org/10.1158/1541-7786.MCR-21-0775