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Pan-Cancer Analysis Reveals Recurrent BCAR4 Gene Fusions across Solid Tumors
Chromosomal rearrangements often result in active regulatory regions juxtaposed upstream of an oncogene to generate an expressed gene fusion. Repeated activation of a common downstream partner–with differing upstream regions across a patient cohort–suggests a conserved oncogenic role. Analysis of 9,...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530645/ https://www.ncbi.nlm.nih.gov/pubmed/35852383 http://dx.doi.org/10.1158/1541-7786.MCR-21-0775 |