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Perioperative stress prolong post-surgical pain via miR-339-5p targeting (oprm1) in the amygdala
BACKGROUND: The decreased expression of mu-opioid receptors (MOR) in the amygdala may be a key molecular in chronic post-surgical pain (CPSP). It is known that miR-339-5p expression in the amygdala of a stressed rat model was increased. Analyzed by RNAhybrid, miR-339-5p could target opioid receptor...
Autores principales: | Zhu, Yi, Sun, Mei, Liu, Peng, Shao, Weidong, Xiong, Ming, Xu, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Pain Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530683/ https://www.ncbi.nlm.nih.gov/pubmed/36175341 http://dx.doi.org/10.3344/kjp.2022.35.4.423 |
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