Enforcing GLUT3 expression in CD8(+) T cells improves fitness and tumor control by promoting glucose uptake and energy storage

Despite the tremendous success of adoptive T-cell therapies (ACT) in fighting certain hematologic malignancies, not all patients respond, a proportion experience relapse, and effective ACT of most solid tumors remains elusive. In order to improve responses to ACT suppressive barriers in the solid tu...

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Detalles Bibliográficos
Autores principales: Cribioli, Elisabetta, Giordano Attianese, Greta Maria Paola, Ginefra, Pierpaolo, Signorino-Gelo, Amandine, Vuillefroy de Silly, Romain, Vannini, Nicola, Hess, Christoph, Irving, Melita, Coukos, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530831/
https://www.ncbi.nlm.nih.gov/pubmed/36203587
http://dx.doi.org/10.3389/fimmu.2022.976628

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